5 aminosalicylic acid (mesalamine)

Administration Instructions, Evaluate renal function prior to initiation of mesalamine delayed-release tablets and periodically while on therapy., Swallow mesalamine delayed-release tablets whole; do not split or crush., Administer mesalamine delayed-release tablets with food., Drink an adequate amount of fluids. Adults, The recommended dosage for the induction of remission in adult patients with mildly to moderately active ulcerative colitis is 2.4 g to 4.8 g (two to four 1.2 g tablets) taken once daily., The recommended dosage for the maintenance of remission is 2.4 g (two 1.2 g tablets) taken once daily.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Mesalamine is contraindicated in patients with known or suspected hypersensitivity to salicylates, aminosalicylates, or to any of the ingredients of mesalamine. Known or suspected hypersensitivity to salicylates or aminosalicylates or to any of the ingredients of mesalamine.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Renal Impairment: Assess renal function at the beginning of treatment and periodically during treatment. Evaluate the risks and benefits of mesalamine in patients with known renal impairment or taking nephrotoxic drugs. Discontinue mesalamine if renal function deteriorates while on therapy., Mesalamine-Induced Acute Intolerance Syndrome: Symptoms may be difficult to distinguish from an ulcerative colitis exacerbation. Monitor for worsening symptoms while on treatment.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

The following clinically significant adverse reactions are described elsewhere in labeling: Renal impairment, including renal failure, Mesalamine-induced acute intolerance syndrome, Hypersensitivity reactions, Hepatic failure, Severe cutaneous adverse reactions, Upper gastrointestinal tract obstruction, Photosensitivity, Nephrolithiasis Most common adverse reactions in: adults (≥2%) are headache, flatulence, liver function…

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

4 products from 2 makers in the NepalDoc medicine catalog use this generic:

Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Store at 20°C to 25°C (68°F to 77°F).

Storage information from the U.S. FDA-approved label.