Abacavir (ABC)

Before initiating TRIUMEQ or TRIUMEQ PD, screen for the HLA‑B*5701 allele because TRIUMEQ and TRIUMEQ PD contain abacavir.., Prior to or when initiating TRIUMEQ or TRIUMEQ PD, test patients for HBV infection., TRIUMEQ and TRIUMEQ PD may be taken with or without food., Adults: One tablet of TRIUMEQ daily. ABC = abacavir, DTG = dolutegravir, 3TC = lamivudine.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

TRIUMEQ and TRIUMEQ PD are contraindicated in patients: who have the HLA-B*5701 allele., with prior hypersensitivity reaction to abacavir, dolutegravir, or lamivudine., receiving dofetilide due to the potential for increased dofetilide plasma concentrations and the risk for serious and/or life-threatening events with concomitant use of dolutegravir., with moderate or severe hepatic impairment., Presence of HLA-B*5701 allele., Prior hypersensitivity reaction to abacavir, dolutegravir, or lamivudine., Coadministration with dofetilide., Moderate or severe hepatic impairment.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Hepatotoxicity has been reported in patients receiving a dolutegravir-containing regimen. Monitoring for hepatotoxicity is recommended., Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported with the use of nucleoside analogues., Immune reconstitution syndrome has been reported in patients treated with combination antiretroviral therapy., TRIUMEQ tablets and TRIUMEQ PD tablets for oral suspension are not substitutable.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

The following adverse reactions are discussed in other sections of the labeling: Serious and sometimes fatal hypersensitivity reaction., Exacerbations of hepatitis B., Hepatotoxicity., Lactic acidosis and severe hepatomegaly with steatosis., Immune reconstitution syndrome., Myocardial infarction.

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

3 products from 3 makers in the NepalDoc medicine catalog use this generic:

Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Store and dispense in the original package, protect from moisture, and keep the bottle tightly closed. Store at 20°C to 25°C (68°F to 77°F); Store at 20°C to 25°C (68°F to 77°F);

Storage information from the U.S. FDA-approved label.