Acarbose

There is no fixed dosage regimen for the management of diabetes mellitus with acarbose tablets or any other pharmacologic agent. Dosage of acarbose tablets must be individualized on the basis of both effectiveness and tolerance while not exceeding the maximum recommended dose of 100 mg t.i.d. Acarbose tablets should be taken three times daily at the start (with the first bite) of each main meal.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Acarbose tablets are contraindicated in patients with known hypersensitivity to the drug. Acarbose tablets are contraindicated in patients with diabetic ketoacidosis or cirrhosis. Acarbose tablets are also contraindicated in patients with inflammatory bowel disease, colonic ulceration, partial intestinal obstruction or in patients predisposed to intestinal obstruction.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

General Macrovascular Outcomes There have been no clinical studies establishing conclusive evidence of macrovascular risk reduction with acarbose tablets or any other anti-diabetic drug. Hypoglycemia Because of its mechanism of action, acarbose tablets when administered alone should not cause hypoglycemia in the fasted or postprandial state. Sulfonylurea agents or insulin may cause hypoglycemia. Because acarbose given in combination with a sulfonylurea or insulin will cause a further lowering of blood glucose, it may increase the potential for hypoglycemia.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

Digestive Tract Gastrointestinal symptoms are the most common reactions to acarbose tablets. In U.S. placebo-controlled trials, the incidences of abdominal pain, diarrhea, and flatulence were 19%, 31%, and 74% respectively in 1255 patients treated with acarbose tablets 50-300 mg t.i.d., whereas the corresponding incidences were 9%, 12%, and 29% in 999 placebo-treated patients.

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

87 products from 51 makers in the NepalDoc medicine catalog use this generic:

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Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Protect from moisture. Keep container tightly closed.

Storage information from the U.S. FDA-approved label.