Bendamustine hydrochloride for Injection is an alkylating drug indicated for treatment of patients with: Chronic lymphocytic leukemia (CLL). Efficacy relative to first line therapies other than chlorambucil has not been established.
From the U.S. FDA-approved label for Bendamustine. Full label: DailyMed.
Bendamustine hydrochloride for Injection is an alkylating drug indicated for treatment of patients with: Chronic lymphocytic leukemia (CLL). Efficacy relative to first line therapies other than chlorambucil has not been established. Indolent B-cell non-Hodgkin lymphoma (NHL) that has progressed during or within six months of treatment with rituximab or a rituximab-containing regimen.
From the U.S. FDA-approved label for Bendamustine. Full label: DailyMed.
Bendamustine hydrochloride is available in two formulations, a solution (Bendamustine Hydrochloride Injection) and a lyophilized powder (Bendamustine Hydrochloride for Injection).
Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.
Bendamustine hydrochloride for Injection is contraindicated in patients with a known hypersensitivity (e.g., anaphylactic and anaphylactoid reactions) to bendamustine. Bendamustine hydrochloride for Injection is contraindicated in patients with a history of a hypersensitivity reaction to bendamustine. Reactions have included anaphylaxis and anaphylactoid reactions.
Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.
Myelosuppression: Delay or reduce dose and restart treatment based on ANC and platelet count recovery. Infections: Monitor for fever and other signs of infection or reactivation of infections and treat promptly. Progressive multifocal leukoencephalopathy (PML): Monitor for new or worsening neurological, cognitive or behavioral signs or symptoms suggestive of PML. Anaphylaxis and Infusion Reactions: Severe and anaphylactic reactions have occurred; monitor clinically and discontinue drug for severe reactions. Pre-medicate in subsequent cycles for milder reactions.
Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.
The following clinically significant adverse reactions have been associated with bendamustine hydrochloride in clinical trials and are discussed in greater detail in other sections of the label.
Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.
23 products from 20 makers in the NepalDoc medicine catalog use this generic:
| Brand | Composition | Maker | Pack |
|---|---|---|---|
| Adben 100mg Injection | Bendamustine (100mg) | Adley Formulations | vial of 1 Injection |
| Bedamax 100 Injection | Bendamustine (100mg) | GLS Pharma Ltd. | vial of 1 Powder for Injection |
| Bendamax 100 Injection | Bendamustine (100mg) | GLS Pharma Ltd. | vial of 1 Injection |
| Bendashil 100mg Injection | Bendamustine (100mg) | Shilpa Medicare Ltd | vial of 1 Injection |
| Bendawel 100mg Injection | Bendamustine (100mg) | Getwell Pharmaceutical Pvt Ltd | vial of 1 Injection |
| Bendit 100mg Injection | Bendamustine (100mg) | Natco Pharma Ltd | vial of 1 Injection |
| Benzz 100mg Injection | Bendamustine (100mg) | Intas Pharmaceuticals Ltd | vial of 1 ml Injection |
| Benzz 180 Injection | Bendamustine (90mg/ml) | Intas Pharmaceuticals Ltd | vial of 2 ml Injection |
| Benzz 45mg Injection | Bendamustine (45mg) | Intas Pharmaceuticals Ltd | vial of 1 Injection |
| Bimode 100mg Injection | Bendamustine (100mg) | Emcure Pharmaceuticals Ltd | vial of 20 ml Injection |
| Bizisa Injection | Bendamustine (100mg) | Zydus Cadila | vial of 1 Injection |
| Cytobendoma 100mg Injection | Bendamustine (100mg) | Alkem Laboratories Ltd | vial of 1 Injection |
| Endamust 100mg Injection | Bendamustine (100mg) | Aureate Healthcare Pvt Ltd | vial of 1 Injection |
| Genmus 100mg Injection | Bendamustine (100mg) | Innova Formulations Pvt Ltd | vial of 1 Injection |
| Leuben Injection | Bendamustine (100mg) | Hetero Drugs Ltd | vial of 1 Powder for Injection |
| Lymphtor 100mg Injection | Bendamustine (100mg) | Torrent Pharmaceuticals Ltd | vial of 1 Injection |
| Maxtorin 100mg Injection | Bendamustine (100mg) | Pfizer Ltd | vial of 20 ml Injection |
| MyMust Injection | Bendamustine (100mg) | Mylan Pharmaceuticals Pvt Ltd | vial of 1 Powder for Injection |
| Neomustin Injection | Bendamustine (100mg) | RPG Life Sciences Ltd | vial of 1 Injection |
| Nexben 100mg Injection | Bendamustine (100mg) | Celon Laboratories Ltd | vial of 1 Injection |
| Purplz 100mg Injection | Bendamustine (100mg) | Dr Reddy's Laboratories Ltd | vial of 1 Injection |
| Ribomustin Injection | Bendamustine (100mg) | Janssen Pharmaceuticals | vial of 1 ml Powder for Injection |
| Xnta 100mg Injection | Bendamustine (100mg) | Biocon | vial of 1 Injection |
Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.
Storage Bendamustine hydrochloride for Injection, USP (25 mg/vial or 100 mg/vial lyophilized powder) Bendamustine hydrochloride for Injection, USP may be stored up to 25°C (77°F) with excursions permitted up to 30°C (86°F) (see USP Controlled Room Temperature). Protect from light.
Storage information from the U.S. FDA-approved label.
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.
