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Benzylpenicillin (penicillin G)

Anti-Infective Medicines
Powder · Injection300 mg · 600 mg30 brands · 7 makers
Benzylpenicillin (penicillin G) is listed in Nepal's National List of Essential Medicines (NLEM, Sixth Revision 2021) under Anti-Infective Medicines. 30 brand names for this medicine are listed in the NepalDoc medicine catalog.
Generic namebenzylpenicillin (penicillin G)
Therapeutic classAnti-Infective Medicines > 6.2.1 Access group antibiotics
Form & strength (NLEM)Powder for injection: 300 mg (= 0.5 million IU), 600 mg (=1 million IU) (as sodium or potassium salt) in vial
Source / स्रोतNational List of Essential Medicines Nepal (2021); NepalDoc medicine catalog

What it's for

Therapy Penicillin G Potassium for Injection, USP is indicated in the treatment of serious infections caused by susceptible strains of the designated microorganisms in the conditions listed below. Appropriate culture and susceptibility tests should be done before treatment in order to isolate and identify organisms causing infection and to determine their susceptibility to penicillin G.

From the U.S. FDA-approved label for Benzylpenicillin (penicillin G). Full label: DailyMed.

Therapy Penicillin G Potassium for Injection, USP is indicated in the treatment of serious infections caused by susceptible strains of the designated microorganisms in the conditions listed below. Appropriate culture and susceptibility tests should be done before treatment in order to isolate and identify organisms causing infection and to determine their susceptibility to penicillin G. Therapy with Penicillin G Potassium for Injection, USP may be initiated before results of such tests are known when there is reason to believe the infection may involve any of the organisms listed below; however, once these results become available, appropriate therapy should be continued.

From the U.S. FDA-approved label for Benzylpenicillin (penicillin G). Full label: DailyMed.

Penicillin G Potassium for Injection, USP may be given intravenously or intramuscularly. The usual dose recommendations are as follows: Adult patients (*) Because of its short half-life, Penicillin G is administered in divided doses, usually every 4 to 6 hours with the exception of meningococcal meningitis/septicemia, i.e., every 2 hours. CLINICAL INDICATION DOSAGE Serious infections due to susceptible strains of streptococci (including S.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

A history of a hypersensitivity (anaphylactic) reaction to any penicillin is a contraindication.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients on penicillin therapy. These reactions are more likely to occur in individuals with a history of penicillin hypersensitivity and/or a history of sensitivity to multiple allergens. There have been reports of individuals with a history of penicillin hypersensitivity who have experienced severe reactions when treated with cephalosporins. Before initiating therapy with penicillin G, careful inquiry should be made concerning previous hypersensitivity reactions to penicillins, cephalosporins, or other allergens.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

Body as a whole The Jarisch-Herxheimer reaction is a systemic reaction, that may occur after the initiation of penicillin therapy in patients with syphilis or other spirochetal infections (i.e., Lyme disease and Relapsing fever). The reaction begins one to two hours after initiation of therapy and disappears within 12 to 24 hours.

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

30 products from 7 makers in the NepalDoc medicine catalog use this generic:

BrandCompositionMakerPack
Benzylpenicillin 1000000IU InjectionPenicillin G (1000000IU)Alembic Pharmaceuticals Ltdvial of 1 Injection
Benzylpenicillin 500000IU InjectionPenicillin G (500000IU)Alembic Pharmaceuticals Ltdvial of 1 Injection
Bistrepen 2000000IU InjectionPenicillin G (2000000IU)Alembic Pharmaceuticals Ltdvial of 5 injections
Bistrepen 400000IU InjectionPenicillin G (400000IU)Alembic Pharmaceuticals Ltdvial of 1 Injection
Bistrepen Forte 200000IU InjectionPenicillin G (200000IU)Alembic Pharmaceuticals Ltdvial of 1 Injection
Bistrepen New Forte InjectionPenicillin G (NA)Alembic Pharmaceuticals Ltdvial of 1 Injection
Bistrepen Paed 200000IU InjectionPenicillin G (200000IU)Alembic Pharmaceuticals Ltdvial of 1 Injection
BP 1200000IU InjectionPenicillin G (1200000IU)Karnataka Antibiotics & Pharmaceuticals Ltdvial of 1 Injection
BP 600000IU InjectionPenicillin G (600000IU)Karnataka Antibiotics & Pharmaceuticals Ltdvial of 1 Injection
Bpg 1000000IU InjectionPenicillin G (1000000IU)Alembic Pharmaceuticals Ltdvial of 1 Injection
Bpg 500000IU InjectionPenicillin G (500000IU)Alembic Pharmaceuticals Ltdvial of 1 Injection
F.P.P 1000000IU InjectionPenicillin G (1000000IU)Alembic Pharmaceuticals Ltdvial of 1 ml Injection
F.P.P 400000IU InjectionPenicillin G (400000IU)Alembic Pharmaceuticals Ltdvial of 1 ml Injection
F.P.P 500000IU InjectionPenicillin G (500000IU)Alembic Pharmaceuticals Ltdvial of 1 ml Injection
Fort.Proc.Pen 2000000IU InjectionPenicillin G (2000000IU)Hindustan Antibiotics Ltdvial of 1 Injection
Fortified Procaine Penicillin 1000000IU InjectionPenicillin G (1000000IU)Alembic Pharmaceuticals Ltdpacket of 1 Injection
Fortified Procaine Penicillin 100000IU InjectionPenicillin G (100000IU)Alembic Pharmaceuticals Ltdvial of 1 Injection
Jollpen InjectionPenicillin G (5Lac units)Jolly Healthcarevial of 1 Injection
Longacillin 1200000IU InjectionPenicillin G (1200000IU)Hindustan Antibiotics Ltdvial of 1 Injection
P.P.F 400000IU InjectionPenicillin G (400000IU)Karnataka Antibiotics & Pharmaceuticals Ltdvial of 1 ml Injection
Pentas 200 TabletPenicillin G (200000IU)Intas Pharmaceuticals Ltdstrip of 6 tablets
Pentas 400 TabletPenicillin G (400000IU)Intas Pharmaceuticals Ltdstrip of 6 tablets
Pentas 800 TabletPenicillin G (800000IU)Intas Pharmaceuticals Ltdstrip of 4 tablets
Pentids 200 TabletPenicillin G (200000IU)Abbottstrip of 10 tablets
Pentids 400 TabletPenicillin G (400000IU)Abbottstrip of 10 tablets
Pentids 800 TabletPenicillin G (800000IU)Abbottstrip of 10 tablets
Procaine InjectionPenicillin G (NA)Alembic Pharmaceuticals Ltdvial of 2 ml Injection
Sodicillin 1000000IU InjectionPenicillin G (1000000IU)Hindustan Antibiotics Ltdvial of 1 Injection
Sodicillin 500000IU InjectionPenicillin G (500000IU)Hindustan Antibiotics Ltdvial of 1 Injection
Stanpen 500 TabletPenicillin G (500000IU)Standard Pharmaceuticals Ltdstrip of 6 tablets

Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Conditions Store dry powder at 20º to 25ºC (68º to 77ºF). Sterile constituted solutions may be kept in a refrigerator at 2° to 8°C (36° to 46°F). When refrigerated, penicillin solutions may be stored for seven days without loss of potency. DISCARD UNUSED SOLUTION AFTER 7 DAYS. Sterile, Nonpyrogenic, Preservative-free. The container closure is not made with natural rubber latex.

Storage information from the U.S. FDA-approved label.

Medicines for the same conditions

Benzylpenicillin (penicillin G) is recorded in the NepalDoc medicine catalog for: Meningitis, Anthrax, Community-acquired pneumonia, Bacterial endocarditis, Septicemia, Diphtheria.

For Meningitis: Flucloxacillin, Gentamicin, Meropenem, Rifampicin.

For Anthrax: Benzathine penicillin, Levofloxacin.

For Community-acquired pneumonia: Levofloxacin.

For Bacterial endocarditis: Vancomycin.

For Diphtheria: Benzathine penicillin, Erythromycin.

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+ Safety information

This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.

NepalDoc — Nepal's Healthcare Super-App (Beta) / नेपालको स्वास्थ्य सुपर-एप (बेटा).
Medicine information only — not medical advice. Confirm with a pharmacist or doctor.