Lenalidomide is used for: Myelodysplastic disease; Multiple myeloma.
Recorded in the NepalDoc medicine catalog for Lenalidomide.
Lenalidomide is a thalidomide analogue indicated for the treatment of adult patients with: Multiple myeloma (MM), in combination with dexamethasone. MM, as maintenance following autologous hematopoietic stem cell transplantation (auto-HSCT).
From the U.S. FDA-approved label for Lenalidomide. Full label: DailyMed.
Lenalidomide is a thalidomide analogue indicated for the treatment of adult patients with: Multiple myeloma (MM), in combination with dexamethasone. MM, as maintenance following autologous hematopoietic stem cell transplantation (auto-HSCT). Transfusion-dependent anemia due to low- or intermediate-1-risk myelodysplastic syndromes (MDS) associated with a deletion 5q abnormality with or without additional cytogenetic abnormalities. Mantle cell lymphoma (MCL) whose disease has relapsed or progressed after two prior therapies, one of which included bortezomib. Previously treated marginal zone lymphoma (MZL), in combination with a rituximab product.
From the U.S. FDA-approved label for Lenalidomide. Full label: DailyMed.
MM combination therapy: 25 mg once daily orally on Days 1 to 21 of repeated 28-day cycles.. MM maintenance therapy following auto-HSCT: 10 mg once daily continuously on Days 1 to 28 of repeated 28-day cycles. MDS: 10 mg once daily.
Directions from the U.S. FDA-approved label for Lenalidomide — your doctor or pharmacist may advise differently.
Pregnancy ( Boxed Warning, 4.1, 5.1, 8.1 ). Demonstrated severe hypersensitivity to lenalidomide. 4.1 Pregnancy Lenalidomide capsules can cause fetal harm when administered to a pregnant female. Limb abnormalities were seen in the offspring of monkeys that were dosed with lenalidomide during organogenesis. This effect was seen at all doses tested. Due to the results of this developmental monkey study, and lenalidomide’s structural similarities to thalidomide, a known human teratogen, lenalidomide is contraindicated in females who are pregnant.
Excerpt from the U.S. FDA-approved label for Lenalidomide. Talk to a pharmacist or doctor before use.
Increased Mortality: serious and fatal cardiac adverse reactions occurred in patients with CLL treated with lenalidomide capsules. Second Primary Malignancies (SPM): Higher incidences of SPM were observed in controlled trials of patients with MM receiving lenalidomide capsules. Increased Mortality: Observed in patients with MM when pembrolizumab was added to dexamethasone and a thalidomide analogue. Hepatotoxicity: Hepatic failure including fatalities; monitor liver function. Stop lenalidomide capsules and evaluate if hepatotoxicity is suspected.
Warnings and precautions excerpt from the U.S. FDA-approved label for Lenalidomide — not a complete list. Talk to a pharmacist or doctor before use.
The following clinically significant adverse reactions are described in detail in other sections of the prescribing information: Embryo-Fetal Toxicity Hematologic Toxicity Venous and Arterial Thromboembolism Increased Mortality in Patients with CLL Second Primary Malignancies Increased Mortality in Patients with MM When Pembrolizumab Is Added to a Thalidomide Analogue and Dexamethasone Hepatotoxicity Severe Cutaneous…
Excerpt from the U.S. FDA-approved label for Lenalidomide — not a complete list. Talk to a pharmacist or doctor about side effects.
3 brands · 1 maker in the NepalDoc catalog — see the full Lenalidomide guide →
Storage Store at 20°C to 25°C (68°F to 77°F);
Storage information from the U.S. FDA-approved label for Lenalidomide.
What is Lenzest 10?
Lenzest 10mg Capsule is a Lenalidomide medicine made by Sun Pharmaceutical Industries Ltd. It comes as 10mg Capsule.
What is Lenzest 10 used for?
Lenalidomide is used for Myelodysplastic disease, Multiple myeloma.
What is the generic name of Lenzest 10?
The generic name of Lenzest 10 is Lenalidomide.
Which brands of Lenalidomide are available in Nepal?
3 brands of Lenalidomide are listed in the NepalDoc catalog, from 1 makers — including Lenzest 25mg Tablet, Lenzest 5mg Tablet.
What are the side effects of Lenalidomide?
The following clinically significant adverse reactions are described in detail in other sections of the prescribing information: Embryo-Fetal Toxicity Hematologic Toxicity Venous and Arterial Thromboembolism Increased Mortality in Patients with CLL Second Primary Malignancies Increased Mortality in Patients with MM When Pembrolizumab Is Added to a Thalidomide Analogue and Dexamethasone Hepatotoxicity Severe Cutaneous…
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. A catalog listing does not guarantee that a medicine is in stock at any pharmacy.
