LAMPRENE is an antimycobacterial indicated for the treatment of lepromatous leprosy, including dapsone-resistant lepromatous leprosy and lepromatous leprosy complicated by erythema nodosum leprosum. To prevent the development of drug-resistance, LAMPRENE should be used only as a part of combination therapy for initial treatment of lepromatous leprosy.
From the U.S. FDA-approved label for Clofazimine. Full label: DailyMed.
LAMPRENE is an antimycobacterial indicated for the treatment of lepromatous leprosy, including dapsone-resistant lepromatous leprosy and lepromatous leprosy complicated by erythema nodosum leprosum. To prevent the development of drug-resistance, LAMPRENE should be used only as a part of combination therapy for initial treatment of lepromatous leprosy. For further guidance on the treatment of leprosy, contact the National Hansen’s Disease Clinical Center, Baton Rouge, Louisiana (LA) at (1-800-642-2477) or http://www.hrsa.gov/hansensdisease/clinicalcenter.html.
From the U.S. FDA-approved label for Clofazimine. Full label: DailyMed.
For dapsone-sensitive lepromatous leprosy, 100 mg (two 50 mg capsules) daily with meals as a part of a combination regimen for at least 2 years is recommended. For dapsone-resistant lepromatous leprosy, 100 mg (two 50 mg capsules) daily with meals in combination with one or more other agents for 3 years. For lepromatous leprosy complicated by erythema nodosum leprosum, 100 mg (two 50 mg capsules) to 200 mg (four 50 mg capsules) daily for up to 3 months.
Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.
LAMPRENE is contraindicated in patients with known hypersensitivity to clofazimine or any of the excipients of LAMPRENE. Known hypersensitivity to clofazimine or to any of the excipients of LAMPRENE.
Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.
Abdominal obstruction and other gastrointestinal adverse reactions: LAMPRENE may deposit in intestinal mucosa causing intestinal disturbances, including abdominal obstruction, bleeding, splenic infarction and death. Reduce dose or discontinue LAMPRENE if patient complains of pain in abdomen or other gastrointestinal symptoms. QT prolongation: QT prolongation and Torsade de Pointes may occur with LAMPRENE. Concomitant use with other QT prolonging drugs or bedaquiline may cause additive QT prolongation.
Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.
The following serious adverse reactions are discussed in greater detail in other sections of the labeling: Abdominal Obstruction and Gastrointestinal Adverse Reactions QT Prolongation Skin and Body Fluid Discoloration and Other Skin Reactions Psychological Effects of Skin Discoloration The following adverse reactions associated with the use of LAMPRENE were identified.
Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.
12 products from 7 makers in the NepalDoc medicine catalog use this generic:
| Brand | Composition | Maker | Pack |
|---|---|---|---|
| Clofozine 100 100mg Tablet | Clofazimine (100mg) | Astra Zeneca | |
| Clofozine 50 50mg Tablet | Clofazimine (50mg) | Astra Zeneca | |
| Clofaz 100mg Soft Gelatin Capsule | Clofazimine (100mg) | Genetiac Pharma | strip of 10 soft gelatin capsules |
| Clofaz 50mg Capsule | Clofazimine (50mg) | Genetiac Pharma | strip of 10 capsules |
| Clofozine 100mg Capsule | Clofazimine (100mg) | AstraZeneca | box of 100 capsules |
| Clofozine 50mg Capsule | Clofazimine (50mg) | AstraZeneca | box of 100 capsules |
| Clofros 100mg Capsule | Clofazimine (100mg) | Sangrose Laboratories Pvt Ltd | strip of 10 capsules |
| Clofros 50mg Capsule | Clofazimine (50mg) | Sangrose Laboratories Pvt Ltd | strip of 10 capsules |
| Fazim 50mg Capsule | Clofazimine (50mg) | Lark Laboratories Ltd | strip of 10 capsules |
| Hansepran 100 Capsule | Clofazimine (100mg) | Abbott | strip of 10 capsules |
| Lepromine 100mg Capsule | Clofazimine (100mg) | P & B Pharmaceuticals Ltd | strip of 10 capsules |
| Lepromine 50mg Capsule | Clofazimine (50mg) | P & B Pharmaceuticals Ltd | strip of 10 capsules |
Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.
Protect from moisture.
Storage information from the U.S. FDA-approved label.
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.
