Clozapine orally disintegrating tablets (Clozapine ODT) is an atypical antipsychotic indicated for: Treatment of severely ill patients with schizophrenia who fail to respond adequately to standard antipsychotic treatment.
From the U.S. FDA-approved label for Clozapine. Full label: DailyMed.
Clozapine orally disintegrating tablets (Clozapine ODT) is an atypical antipsychotic indicated for: Treatment of severely ill patients with schizophrenia who fail to respond adequately to standard antipsychotic treatment. Because of the risks of severe neutropenia and of seizure associated with its use, Clozapine ODT should be used only in patients who have failed to respond adequately to standard antipsychotic treatment Reducing the risk of recurrent suicidal behavior in patients with schizophrenia or schizoaffective disorder who are judged to be at chronic risk for re-experiencing suicidal behavior 1.1 Treatment-resistant Schizophrenia Clozapine Orally Disintegrating Tablets (Clozapine ODT) are indicated for the treatment of severely ill patients with schizophrenia who fail to respond adequately to standard antipsychotic treatment. Because of the risks of severe neutropenia and of seizure associated with their use, Clozapine ODT should be used only in patients who have failed to respond adequately to standard antipsychotic treatment.
From the U.S. FDA-approved label for Clozapine. Full label: DailyMed.
Recommended starting oral dosage is 12.5 mg once daily or twice daily. If well-tolerated, increase the total daily dosage in increments of 25 mg to 50 mg per day at target dosage of 150 mg to 225 mg twice per day by the end of two weeks. Subsequently may increase the doage in increments up to 100 mg, once or twice weekly.
Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.
Clozapine ODT is contraindicated in patients with a history of hypersensitivity to clozapine (e.g., photosensitivity, vasculitis, erythema multiforme, or Stevens-Johnson Syndrome) or any other component of Clozapine ODT. Known hypersensitivity to clozapine or any other component of Clozapine ODT
Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.
Severe neutropenia: See Gastrointestinal Hypomotility with Severe Complications: Severe gastrointestinal adverse reactions have occurred with the use of clozapine. If constipation is identified, close monitoring and prompt treatment is advised. Eosinophilia: Assess for organ involvement (e.g., myocarditis, pancreatitis, hepatitis, colitis, nephritis). Discontinue if these occur. QT Interval Prolongation: Can be fatal. Consider additional risk factors for prolonged QT interval (disorders and drugs).
Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.
The following adverse reactions are discussed in more detail in other sections of the labeling: Severe Neutropenia Orthostatic Hypotension, Bradycardia, and Syncope Falls Seizures Myocarditis, Pericarditis, Cardiomyopathy, and Mitral Valve Incompetence Increased Mortality in Elderly Patients with Dementia-Related Psychosis Gastrointestinal Hypomotility with Severe Complications Eosinophilia QT Interval Prolongation Metabolic…
Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.
166 products from 63 makers in the NepalDoc medicine catalog use this generic:
| Brand | Composition | Maker | Pack |
|---|---|---|---|
| Llozapin 100 mg Tablet | Clozapine (100 mg) | Torrent Pharmaceuticals Ltd. | |
| Llozapin 25 mg Tablet | Clozapine (25 mg) | Torrent Pharmaceuticals Ltd. | |
| Lozapin 100mg Tablet | Clozapine (100mg) | Torrent Pharmaceuticals Ltd. | |
| Lozapin 25mg Tablet | Clozapine (25mg) | Torrent Pharmaceuticals Ltd. | |
| Sizomax 100mg Tablet | Clozapine (100mg) | Asian Pharmaceuticals Pvt. Ltd. | |
| Sizopin 100 100mg Tablet | Clozapine (100mg) | Sun Pharmaceutical Industries Ltd. | |
| Sizopin 200mg Tablet | Clozapine (200mg) | Sun Pharmaceutical Industries Ltd. | |
| Sizopin 25 25mg Tablet | Clozapine (25mg) | Sun Pharmaceutical Industries Ltd. | |
| Sizopin 50mg Tablet | Clozapine (50mg) | Sun Pharmaceutical Industries Ltd. | |
| Alkepin 25mg Tablet DT | Clozapine (25mg) | Alkem Laboratories Ltd | strip of 10 tablet dt |
| Alkepin Odt 100mg Tablet | Clozapine (100mg) | Alkem Laboratories Ltd | strip of 10 tablets |
| Alkepin Odt 12.5mg Tablet | Clozapine (12.5mg) | Alkem Laboratories Ltd | strip of 10 tablets |
| Alkepin Odt 200 Tablet | Clozapine (200mg) | Alkem Laboratories Ltd | strip of 10 tablets |
| Alkepin Odt 25mg Tablet | Clozapine (25mg) | Alkem Laboratories Ltd | strip of 10 tablets |
| Alkepin Odt 50mg Tablet | Clozapine (50mg) | Alkem Laboratories Ltd | strip of 10 tablets |
| Catedix 100 Tablet | Clozapine (100mg) | Psychocare Health Pvt Ltd | strip of 10 tablets |
| Catedix 25 Tablet | Clozapine (25mg) | Psychocare Health Pvt Ltd | strip of 10 tablets |
| Catedix 50 Tablet | Clozapine (50mg) | Psychocare Health Pvt Ltd | strip of 10 tablets |
| Chrozap 50mg Tablet | Clozapine (50mg) | Orchid Chemicals & Pharmaceuticals Ltd | strip of 10 tablets |
| Cipin 100mg Tablet | Clozapine (100mg) | D D Pharmaceuticals | strip of 10 tablets |
| Cipin 12.5mg Tablet | Clozapine (12.5mg) | D D Pharmaceuticals | strip of 10 tablets |
| Cipin 200mg Tablet | Clozapine (200mg) | D D Pharmaceuticals | strip of 10 tablets |
| Cipin 25mg Tablet | Clozapine (25mg) | D D Pharmaceuticals | strip of 10 tablets |
| Cipin 50mg Tablet | Clozapine (50mg) | D D Pharmaceuticals | strip of 10 tablets |
| Cizodep 50mg Tablet | Clozapine (50mg) | Regal Pharmaceuticals | strip of 10 tablets |
| Clocer 100mg Tablet | Clozapine (100mg) | Ceras Pharmaceutical | strip of 10 tablets |
| Clocer 25mg Tablet | Clozapine (25mg) | Ceras Pharmaceutical | strip of 10 tablets |
| Clocer 50mg Tablet | Clozapine (50mg) | Ceras Pharmaceutical | strip of 10 tablets |
| Clomach 100mg Tablet | Clozapine (100mg) | La Pharmaceuticals | strip of 10 tablets |
| Clomach 25mg Tablet | Clozapine (25mg) | La Pharmaceuticals | strip of 10 tablets |
Showing 30 of 166 catalog products. Search the full catalog in the app.
Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.
Store at 20° to 25°C (68° to 77°F). Protect from moisture. Keep out of reach of children.
Storage information from the U.S. FDA-approved label.
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. A catalog listing does not guarantee that a medicine is in stock at any pharmacy.
