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Deferiprone

Iron chelator
Tablet500 mg2 brands · 1 maker
Deferiprone is an iron chelator used for the treatment of transfusional iron overload in adult patients with thalassemia syndromes when current chelation therapy is inadequate. Deferiprone is listed in Nepal's National List of Essential Medicines (NLEM, Sixth Revision 2021) under Medicines Affecting the Blood.
Generic namedeferiprone
Therapeutic classMedicines Affecting the Blood > 10.3 Other medicines for haemoglobinopathies (complementary list)
Form & strength (NLEM)Tablet: 500 mg
Source / स्रोतNational List of Essential Medicines Nepal (2021); NepalDoc medicine catalog

What it's for

Deferiprone tablets are indicated for the treatment of transfusional iron overload in adult patients with thalassemia syndromes when current chelation therapy is inadequate.

From the U.S. FDA-approved label for Deferiprone. Full label: DailyMed.

Deferiprone tablets are indicated for the treatment of transfusional iron overload in adult patients with thalassemia syndromes when current chelation therapy is inadequate.

From the U.S. FDA-approved label for Deferiprone. Full label: DailyMed.

Deferiprone Tablets are available in a 1,000 mg formulation., To prevent medication errors, before prescribing and dispensing, ensure that the tablet formulation is appropriate for the dosing regimen.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Deferiprone tablets are contraindicated in patients with known hypersensitivity to deferiprone or to any of the excipients in the formulation. The following reactions have been reported in association with the administration of deferiprone: Henoch-Schönlein purpura; urticaria; and periorbital edema with skin rash. Hypersensitivity to deferiprone or to any of the excipients in the formulations.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Liver Enzyme Elevations: Monitor monthly and discontinue for persistent elevations., Zinc Deficiency: Monitor during therapy and supplement for deficiency., Embryo-Fetal Toxicity: Can cause fetal harm. 5.1 Agranulocytosis and Neutropenia Fatal agranulocytosis can occur with deferiprone tablets use. Deferiprone tablets can also cause neutropenia, which may foreshadow agranulocytosis. Measure the absolute neutrophil count (ANC) before starting deferiprone tablets therapy and monitor it regularly while on therapy.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

The following clinically significant adverse reactions are described below and elsewhere in the labeling: Agranulocytosis and Neutropenia, Liver Enzyme Elevations, Zinc Deficiency, The most common adverse reactions in patients with thalassemia (incidence ≥ 6%) are nausea, vomiting, abdominal pain, arthralgia, ALT increased and neutropenia. To report SUSPECTED ADVERSE REACTIONS, contact Hikma Pharmaceuticals USA Inc.

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

2 products from 1 maker in the NepalDoc medicine catalog use this generic:

BrandCompositionMakerPack
Kelfer 250 CapsuleDeferiprone (250mg)Cipla Ltdbottle of 50 capsules
Kelfer 500 CapsuleDeferiprone (500mg)Cipla Ltdbottle of 50 capsules

Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Storage: Store at 20° to 25°C (68° to 77°F); Keep the bottle tightly closed to protect from moisture.

Storage information from the U.S. FDA-approved label.

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+ Safety information

This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.

NepalDoc — Nepal's Healthcare Super-App (Beta) / नेपालको स्वास्थ्य सुपर-एप (बेटा).
Medicine information only — not medical advice. Confirm with a pharmacist or doctor.