Desmopressin acetate injection is a vasopressin analog used for: Central Diabetes Insipidus - as antidiuretic replacement therapy in the management of central (cranial) diabetes insipidus and for the management of the temporary polyuria and polydipsia following head trauma or surgery in the pituitary region.
From the U.S. FDA-approved label for Desmopressin. Full label: DailyMed.
Desmopressin acetate injection is a vasopressin analog used for: Central Diabetes Insipidus - as antidiuretic replacement therapy in the management of central (cranial) diabetes insipidus and for the management of the temporary polyuria and polydipsia following head trauma or surgery in the pituitary region. Hemophilia A- for patients with factor VIII coagulant activity levels greater than 5% to maintain hemostasis during surgical procedures and postoperatively or reduce bleeding with episodes of spontaneous or traumatic injuries such as hemarthroses, intramuscular hematomas, or mucosal bleeding.
From the U.S. FDA-approved label for Desmopressin. Full label: DailyMed.
Diabetes Insipidus: The daily dose is 2 mcg to 4 mcg administered as one or two divided doses by subcutaneous or intravenous injection. The dosage must be determined for each patient and adjusted according to the pattern of response. Hemophilia A and von Willebrand’s Disease (Type I): 0.3 mcg/kg (to a maximum of 20 mcg) administered by intravenous infusion.
Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.
Desmopressin acetate injection is contraindicated in patients with known hypersensitivity to desmopressin acetate or to any of the components of desmopressin acetate injection. Desmopressin acetate injection is contraindicated in patients with the following conditions due to an increased risk of hyponatremia: Moderate to severe renal impairment defined as a creatinine clearance below 50 mL/min. Hyponatremia or a history of hyponatremia, Use in Specific Populations. Known or suspected syndrome of inappropriate antidiuretic hormone (SIADH) secretion.
Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.
Hypotension and Hypertension: May cause hypotension with compensatory increase in heart rate or hypertension. Monitor blood pressure during desmopressin acetate administration, especially in patients with heart disease. Increased Risk of Thrombosis in Patients with von Willebrand’s Disease Type IIB: Use of desmopressin acetate in patients with Type IIB von Willebrand’s disease may cause thrombosis due to platelet aggregation. Hypersensitivity Reactions: Severe reactions have occurred. Monitor for reactions during administration and interrupt if reaction occurs.
Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.
The following clinically significant adverse reactions are described elsewhere in the labeling: Hyponatremia Hypotension and Hypertension Increased risk of thrombosis in patients with von Willebrand’s Disease Type IIB Hypersensitivity reactions Fluid retention The following adverse reactions have been identified during post-approval use of desmopressin acetate injection.
Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.
13 products from 5 makers in the NepalDoc medicine catalog use this generic:
| Brand | Composition | Maker | Pack |
|---|---|---|---|
| D void N Spray 1mcg/ml Nasal Spray | Desmopressin (1mcg/ml) | Sun Pharmaceutical Industries Ltd. | |
| Minirin 0.1mg Tablet | Desmopressin (0.1mg) | Ferring Pharmaceuticals | |
| Minirin 0.2mg Tablet | Desmopressin (0.2mg) | Ferring Pharmaceuticals | |
| Minirin 10mcg Nasal Spray | Desmopressin (10mcg) | Ferring Pharmaceuticals | |
| Minirin 4mcg Injection | Desmopressin (4mcg) | Ferring Pharmaceuticals | |
| D Void Tablet | Desmopressin (0.2mg) | Sun Pharmaceutical Industries Ltd | strip of 10 tablets |
| Dessin Nasal Spray | Desmopressin (0.01% w/v) | Chemo Healthcare Pvt Ltd | pump bottle of 5 ml Nasal Spray |
| Dpressin 0.1mg Tablet | Desmopressin (0.1mg) | United Biotech Pvt Ltd | strip of 10 tablets |
| Dpressin Nasal Spray | Desmopressin (0.1mg/ml) | United Biotech Pvt Ltd | packet of 5 ml Nasal Spray |
| Minirin Melt 0.1mg Tablet | Desmopressin (0.1mg) | Ferring Pharmaceuticals | strip of 10 tablets |
| Minirin Melt 120mcg Tablet | Desmopressin (120mcg) | Ferring Pharmaceuticals | strip of 10 tablets |
| Minirin Melt 60mcg Tablet MD | Desmopressin (0.06mg) | Ferring Pharmaceuticals | strip of 10 tablet md |
| Minirin Nasal Spray | Desmopressin (0.1mg/ml) | Ferring Pharmaceuticals | packet of 2.5 ml Nasal Spray |
Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.
Store refrigerated 2° to 8°C (36° to 46°F).
Storage information from the U.S. FDA-approved label.
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.
