Digoxin is a cardiac glycoside indicated in adults for the treatment of mild to moderate heart failure and for the control of resting ventricular rate in patients with chronic atrial fibrillation. In pediatric patients with heart failure, digoxin is indicated to increase myocardial contractility.
From the U.S. FDA-approved label for Digoxin. Full label: DailyMed.
Digoxin is a cardiac glycoside indicated in adults for the treatment of mild to moderate heart failure and for the control of resting ventricular rate in patients with chronic atrial fibrillation. In pediatric patients with heart failure, digoxin is indicated to increase myocardial contractility. 1.1 Heart Failure in Adults Digoxin Oral Solution is indicated for the treatment of mild to moderate heart failure. Digoxin increases left ventricular ejection fraction and improves heart failure symptoms as evidenced by increased exercise capacity and decreased heart failure-related hospitalizations and emergency care, while having no effect on mortality. Where possible, digoxin should be used with a diuretic and an angiotensin-converting enzyme inhibitor, but an optimal order for starting these three drugs cannot be specified.
From the U.S. FDA-approved label for Digoxin. Full label: DailyMed.
Toxic levels of digoxin are only slightly higher than therapeutic levels. The pharmacokinetics of digoxin are complex and dose determination should take into account patient-specific factors (age, lean body weight, renal function, etc.). Patients should be monitored for toxicity and therapeutic effect and doses should be adjusted, accordingly.
Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.
Allergy to digoxin is rare. Digoxin is contraindicated in patients with a known hypersensitivity to digoxin or other forms of digitalis. Digitalis glycosides, such as digoxin, are contraindicated in ventricular fibrillation., Known hypersensitivity to digoxin or other forms of digitalis., Ventricular fibrillation.
Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.
Accessory AV Pathway: Increased risk of rapid ventricular response leading to ventricular fibrillation., Sinus Node Disease and AV Block: Digoxin use can exacerbate the condition and may cause advanced or complete heart block., Misidentification of Digoxin Toxicity: Signs and symptoms of digoxin toxicity may be mistaken for worsening symptoms of congestive heart failure., Preserved Left Ventricular Systolic Function: Patients with heart failure with preserved left ventricular ejection fraction may be more susceptible to digoxin toxicity.…
Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.
The frequency and severity of adverse reactions to digoxin when taken orally depend on the dose and the patient's underlying disease or concomitant therapies. The overall incidence of adverse reactions has been reported as 5% to 20%, with 15% to 20% of them being considered serious (1% to 4% of patients receiving digoxin).
Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.
26 products from 16 makers in the NepalDoc medicine catalog use this generic:
| Brand | Composition | Maker | Pack |
|---|---|---|---|
| Cardioxin 0.25mg Tablet | Digoxin (0.25mg) | Novartis India Ltd. | |
| Digicard 0.25mg Tablet | Digoxin (0.25mg) | Omnica Laboratories Pvt. Ltd.. | |
| Digoxin Injection | Digoxin | Samarth Life Sciences Pvt Ltd | |
| Dixin 0.25mg Tablet | Digoxin (0.25mg) | Samarth Life Sciences Pvt Ltd | |
| Dixin 0.5 mg Injection | Digoxin (0.5 mg) | Samarth Life Sciences Pvt Ltd | |
| Lanoxin 0.25mg Tablet | Digoxin (0.25mg) | Glaxo SmithKline Pharmaceuticals Ltd. | |
| Myoxin 0.125mg Tablet | Digoxin (0.125mg) | Vega Pharma | |
| Myoxin 0.25mg Tablet | Digoxin (0.25mg) | Vega Pharma | |
| Canrythm 0.25mg Tablet | Digoxin (0.25mg) | Canipla Care | strip of 10 tablets |
| Cardin 0.25mg Tablet | Digoxin (0.25mg) | Chemo Biological | strip of 10 tablets |
| Cardisip Syrup | Digoxin (3mg) | Alixinox Pharmaceuticals | bottle of 60 ml Syrup |
| Caxin 0.25mg Tablet | Digoxin (0.25mg) | East West Pharma | strip of 10 tablets |
| Digitran 0.25mg Tablet | Digoxin (0.25mg) | Macleods Pharmaceuticals Pvt Ltd | strip of 10 tablets |
| Digon Tablet | Digoxin (0.25mg) | Tas Med India Pvt Ltd | strip of 10 tablets |
| Digover 0.25mg Tablet | Digoxin (0.25mg) | Clover Health Care Pharma | strip of 10 tablets |
| Digoxin 50mcg/ml Elixir | Digoxin (50mcg/ml) | Glaxo SmithKline Pharmaceuticals Ltd | bottle of 30 elixirs |
| Dixin 0.25mg Injection | Digoxin (0.25mg) | Samarth Life Sciences Pvt Ltd | vial of 2 injections |
| Dixin 3mg Syrup | Digoxin (3mg) | Samarth Life Sciences Pvt Ltd | bottle of 60 ml Syrup |
| Dixin Paed Oral Solution | Digoxin (50mcg/ml) | Samarth Life Sciences Pvt Ltd | bottle of 60 ml Oral Solution |
| Dixin Tablet | Digoxin (0.25mg) | Samarth Life Sciences Pvt Ltd | strip of 10 tablets |
| Geoxin 0.25mg Tablet | Digoxin (0.25mg) | Geo Pharma Pvt Ltd | strip of 10 tablets |
| Geoxin 0.5mg Injection | Digoxin (0.5mg) | Geo Pharma Pvt Ltd | vial of 2 ml Injection |
| Lanoxin Syrup | Digoxin (1% w/v) | Glaxo SmithKline Pharmaceuticals Ltd | bottle of 30 ml Syrup |
| Lanoxin Tablet | Digoxin (0.25mg) | Glaxo SmithKline Pharmaceuticals Ltd | strip of 10 tablets |
| Lidoxin 0.25mg Tablet | Digoxin (0.25mg) | Johnlee Pharmaceuticals Pvt Ltd | strip of 10 tablets |
| Sangoxin 0.25mg Tablet | Digoxin (0.25mg) | Sanofi India Ltd | strip of 14 tablets |
Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.
Storage Store at 20° to 25°C (68° to 77°F). Protect from light.
Storage information from the U.S. FDA-approved label.
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.
