Divalproex sodium delayed-release tablets are an anti-epileptic drug indicated for: Treatment of manic episodes associated with bipolar disorder Monotherapy and adjunctive therapy of complex partial seizures and simple and complex absence seizures; adjunctive therapy in patients with multiple seizure types that include absence seizures Prophylaxis of migraine headaches 1.1 Mania Divalproex sodium is a valproate and is indicated for the treatment of the manic episodes associated with bipolar disorder.
From the U.S. FDA-approved label for Divalproex. Full label: DailyMed.
Divalproex sodium delayed-release tablets are an anti-epileptic drug indicated for: Treatment of manic episodes associated with bipolar disorder Monotherapy and adjunctive therapy of complex partial seizures and simple and complex absence seizures; adjunctive therapy in patients with multiple seizure types that include absence seizures Prophylaxis of migraine headaches 1.1 Mania Divalproex sodium is a valproate and is indicated for the treatment of the manic episodes associated with bipolar disorder. A manic episode is a distinct period of abnormally and persistently elevated, expansive, or irritable mood. Typical symptoms of mania include pressure of speech, motor hyperactivity, reduced need for sleep, flight of ideas, grandiosity, poor judgment, aggressiveness, and possible hostility. The efficacy of divalproex sodium delayed-release tablets was established in 3-week trials with patients meeting DSM-III-R criteria for bipolar disorder who were hospitalized for acute mania. The safety and effectiveness of divalproex sodium delayed-release tablets for long-term use in mania, i.e., more than 3 weeks, has not been demonstrated in controlled clinical trials.
From the U.S. FDA-approved label for Divalproex. Full label: DailyMed.
Divalproex sodium delayed-release tablets are intended for oral administration. Patients should be informed to take divalproex sodium delayed-release tablets every day as prescribed. If a dose is missed it should be taken as soon as possible, unless it is almost time for the next dose.
Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.
Divalproex sodium delayed-release tablets should not be administered to patients with hepatic disease or significant hepatic dysfunction. Divalproex sodium delayed-release tablets are contraindicated in patients known to have mitochondrial disorders caused by mutations in mitochondrial DNA polymerase γ (POLG; e.g., Alpers-Huttenlocher Syndrome) and children under two years of age who are suspected of having a POLG-related disorder. Divalproex sodium delayed-release tablets are contraindicated in patients with known hypersensitivity to the drug.
Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.
Hepatotoxicity; evaluate high risk populations and monitor serum liver tests Birth defects, decreased IQ, and neurodevelopmental disorders following in utero exposure; should not be used to treat women with epilepsy or bipolar disorder who are pregnant or who plan to become pregnant or to treat a woman of childbearing potential unless other medications have failed to provide adequate symptom control or are otherwise unacceptable Pancreatitis; divalproex sodium delayed-release tablets should ordinarily be discontinued Suicidal behavior or ideation; Antiepileptic drugs…
Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.
The following serious adverse reactions are described below and elsewhere in the labeling: Hepatic failure Birth defects Decreased IQ following in utero exposure Pancreatitis Hyperammonemic encephalopathy Suicidal behavior and ideation Bleeding and other hematopoietic disorders Hypothermia Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)/Multiorgan hypersensitivity reactions Somnolence in the elderly Because…
Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.
489 products from 208 makers in the NepalDoc medicine catalog use this generic:
| Brand | Composition | Maker | Pack |
|---|---|---|---|
| Adival 125mg Tablet ER | Divalproex (125mg) | Lotus Life Sciences | strip of 10 tablet er |
| Adival 250mg Tablet ER | Divalproex (250mg) | Lotus Life Sciences | strip of 10 tablet er |
| Adival 500mg Tablet ER | Divalproex (500mg) | Lotus Life Sciences | strip of 10 tablet er |
| Adreval 1000mg Tablet ER | Divalproex (1000mg) | Adrena Healthcare Pvt Ltd | strip of 10 tablet er |
| Alodium 500mg Tablet XR | Divalproex (500mg) | Enrico Pharmaceuticals | strip of 10 tablet xr |
| Alporate D 250mg Tablet | Divalproex (250mg) | Alteus Biogenics Pvt Ltd | strip of 15 tablets |
| Alporate D 500mg Tablet ER | Divalproex (500mg) | Alteus Biogenics Pvt Ltd | strip of 15 tablet er |
| Alporate Syrup | Divalproex (250mg/5ml) | Alteus Biogenics Pvt Ltd | bottle of 200 ml Oral Solution |
| Ardiva 250mg Tablet ER | Divalproex (250mg) | Arpsy Life Science Private Limited | strip of 10 tablet er |
| Avelap 250mg Tablet SR | Divalproex (250mg) | Athens Labs Ltd | strip of 10 tablet sr |
| Avelap 500mg Tablet SR | Divalproex (500mg) | Athens Labs Ltd | strip of 10 tablet sr |
| Behav 500mg Tablet ER | Divalproex (500mg) | Naj Pharmaceuticals Private Limited | strip of 10 tablet er |
| Binaprex 1000mg Tablet ER | Divalproex (1000mg) | CNX Healthcare Pvt Ltd | strip of 10 tablet er |
| Binaprex 250mg Tablet ER | Divalproex (250mg) | Cenesys Care India Pvt Ltd | strip of 10 tablet er |
| Binaprex 500mg Tablet ER | Divalproex (500mg) | Cenesys Care India Pvt Ltd | strip of 10 tablet er |
| Binaprex 750mg Tablet ER | Divalproex (750mg) | CNX Healthcare Pvt Ltd | strip of 10 tablet er |
| Biovalp 250mg Tablet ER | Divalproex (250mg) | Bioris Pharmaceuticals | strip of 10 tablet er |
| Biovalp 500mg Tablet ER | Divalproex (500mg) | Bioris Pharmaceuticals | strip of 10 tablet er |
| Brisval 250mg Tablet ER | Divalproex (250mg) | Madbris Life Sciences Pvt Ltd | strip of 10 tablet er |
| Brisval 500mg Tablet ER | Divalproex (500mg) | Madbris Life Sciences Pvt Ltd | strip of 10 tablet er |
| Bypol 250 Tablet | Divalproex (250mg) | MSN Laboratories | strip of 10 tablets |
| Bypol 500mg Tablet | Divalproex (500mg) | MSN Laboratories | strip of 10 tablets |
| Bypol-OD 250 Tablet ER | Divalproex (250mg) | MSN Laboratories | strip of 10 tablet er |
| Bypol-OD 500 Tablet ER | Divalproex (500mg) | MSN Laboratories | strip of 10 tablet er |
| Cognirex-OD 250mg Tablet | Divalproex (250mg) | Evaxo Pharma | strip of 10 tablets |
| Cognirex-OD 500 Tablet PR | Divalproex (500mg) | Evaxo Pharma | strip of 10 Tablet pr |
| Cylenc DS 250mg Tablet | Divalproex (250mg) | D.S. Lab | strip of 10 tablets |
| Cylenc DS 500mg Tablet | Divalproex (500mg) | D.S. Lab | strip of 10 tablets |
| D-Valprax 250 ER Tablet | Divalproex (250mg) | Avallac Pharmaceutical LLP | strip of 10 tablet er |
| D-Valprax 500 ER Tablet | Divalproex (500mg) | Avallac Pharmaceutical LLP | strip of 10 tablet er |
Showing 30 of 489 catalog products. Search the full catalog in the app.
Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.
Store at 20° to 25°C (68° to 77°F); excursions permitted to 15° to 30°C (59° to 86°F). Dispense in a tight, light-resistant container with a child-resistant closure.
Storage information from the U.S. FDA-approved label.
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. A catalog listing does not guarantee that a medicine is in stock at any pharmacy.
