Duloxetine

Take duloxetine delayed-release capsules once daily, with or without food.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

The use of MAOIs intended to treat psychiatric disorders with duloxetine or within 5 days of stopping treatment with duloxetine is contraindicated because of an increased risk of serotonin syndrome. The use of duloxetine within 14 days of stopping an MAOI intended to treat psychiatric disorders is contraindicated. Starting duloxetine in a patient who is being treated with MAOIs such as linezolid or intravenous methylene blue is also contraindicated because of an increased risk of serotonin syndrome.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Hepatotoxicity: Hepatic failure, sometimes fatal, has been reported. Discontinue duloxetine in patients who develop jaundice or other evidence of clinically significant liver dysfunction and should not be resumed unless another cause can be established. Avoid use in patients with substantial alcohol use or evidence of chronic liver disease Orthostatic Hypotension, Falls and Syncope: Consider dosage reduction or discontinuation if these events occur Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents but also when taken alone.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

The following serious adverse reactions are described below and elsewhere in the labeling: Suicidal Thoughts and Behaviors in Children, Adolescents and Young Adults Hepatotoxicity Orthostatic Hypotension, Falls and Syncope Serotonin Syndrome Increased Risk of Bleeding Severe Skin Reactions Discontinuation Syndrome Activation of Mania/Hypomania Angle-Closure Glaucoma Seizures Increases in Blood Pressure Clinically Important…

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

319 products from 159 makers in the NepalDoc medicine catalog use this generic:

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Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Store at 25°C (77°F);

Storage information from the U.S. FDA-approved label.