Fentanyl transdermal system is indicated for the management of severe and persistent pain in opioid-tolerant patients, that requires an opioid analgesic and that cannot be adequately treated with alternative options, including immediate-release opioids.
From the U.S. FDA-approved label for Fentanyl. Full label: DailyMed.
Fentanyl transdermal system is indicated for the management of severe and persistent pain in opioid-tolerant patients, that requires an opioid analgesic and that cannot be adequately treated with alternative options, including immediate-release opioids. Patients considered opioid-tolerant are those who are taking, for one week or longer, at least 60 mg morphine per day, 25 mcg transdermal fentanyl per hour, 30 mg oral oxycodone per day, 8 mg oral hydromorphone per day, 25 mg oral oxymorphone per day, 60 mg oral hydrocodone per day, or an equianalgesic dose of another opioid.
From the U.S. FDA-approved label for Fentanyl. Full label: DailyMed.
Fentanyl transdermal system should be prescribed only by healthcare providers who are knowledgeable about the use of extended-release/long-acting opioids and how to mitigate the associated risks. Use the lowest effective dosage for the shortest duration of time consistent with individual patient treatment goals. Reserve titration to higher doses of fentanyl transdermal system for patients in whom lower doses are insufficiently effective and in whom the expected benefits of using a higher dose opioid clearly outweigh the substantial risks.
Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.
Fentanyl transdermal system is contraindicated in: patients who are not opioid-tolerant. the management of acute or intermittent pain, or in patients who require opioid analgesia for a short period of time. the management of post-operative pain, including use after outpatient or day surgeries, (e.g., tonsillectomies). the management of mild pain. patients with significant respiratory depression. patients with acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment.
Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.
Risk of Increased Fentanyl Absorption with Elevated Body Temperature: Regularly evaluate patients with fever closely for sedation and respiratory depression and reduce the dose if necessary. Warn patients to avoid strenuous exertion that may lead to increased body temperature. Opioid Induced Hyperalgesia (OIH) and Allodynia: Opioid-Induced Hyperalgesia (OIH) occurs when an opioid analgesic paradoxically causes an increase in pain, or an increase in sensitivity to pain. If OIH is suspected, carefully consider appropriately decreasing the dose of the current opioid analgesic, or opioid rotation.
Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.
The following serious adverse reactions are discussed elsewhere in the labeling: Addiction, Abuse, and Misuse Life-Threatening Respiratory Depression Accidental Exposure Interactions with Benzodiazepines or Other Central Nervous System Depressants Neonatal Opioid Withdrawal Syndrome Opioid-Induced Hyperalgesia and Allodynia Serotonin Syndrome Adrenal Insufficiency Severe Hypotension Gastrointestinal Adverse Reactions Seizures…
Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.
18 products from 11 makers in the NepalDoc medicine catalog use this generic:
| Brand | Composition | Maker | Pack |
|---|---|---|---|
| Fendrop 50mcg Injection | Fentanyl (50mcg) | Sun Pharmaceutical Industries Ltd. | |
| Fentanyl 50mcg/1ml Injection | Fentanyl (50mcg/1ml) | Sun Pharmaceutical Industries Ltd. | |
| Fentyl 50mcg Injection | Fentanyl (50mcg) | National Healthcare Pvt. Ltd. | |
| Durogesic 25mcg Patch | Fentanyl (25mcg) | Janssen Pharmaceuticals | packet of 3 transdermal patches |
| Durogesic 50mcg Patch | Fentanyl (50mcg) | Janssen Pharmaceuticals | packet of 3 transdermal patches |
| Fendrop 25mcg Patch | Fentanyl (25mcg) | Sun Pharmaceutical Industries Ltd | packet of 1 Transdermal Patch |
| Fendrop 50mcg Patch | Fentanyl (50mcg) | Sun Pharmaceutical Industries Ltd | packet of 1 Transdermal Patch |
| Fenspar 12.5mg Patch | Fentanyl (12.5mg) | Sparsha Pharma International Pvt Ltd | box of 3 patches |
| Fenspar 25mg Patch | Fentanyl (25mg) | Sparsha Pharma International Pvt Ltd | box of 3 patches |
| Fenspar 50mg Patch | Fentanyl (50mg) | Sparsha Pharma International Pvt Ltd | box of 3 patches |
| Fenstud 50mcg Injection | Fentanyl (50mcg) | Rusan Pharma Ltd | vial of 2 ml Injection |
| Fent 50mcg Injection | Fentanyl (50mcg) | Neon Laboratories Ltd | vial of 2 ml Injection |
| Fentrans 25mcg Transdermal Patch | Fentanyl (25mcg) | 6ipain Healthcare Pvt Ltd | box of 3 transdermal patches |
| Fentrans 50mcg Transdermal Patch | Fentanyl (50mcg) | 6ipain Healthcare Pvt Ltd | box of 3 transdermal patches |
| Opifent 100 Injection | Fentanyl (50mcg) | Varenyam Healthcare Pvt Ltd | ampoule of 2 ml Injection |
| Opifent 500 Injection | Fentanyl (50mcg) | Varenyam Healthcare Pvt Ltd | ampoule of 10 ml Injection |
| Trofentyl 50mcg Injection | Fentanyl (50mcg) | Troikaa Pharmaceuticals Ltd | ampoule of 10 ml Injection |
| Verfen Injection | Fentanyl (50mcg) | Verve Healthcare Ltd | ampoule of 10 ml Injection |
Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.
Store up to 25°C (77°F);
Storage information from the U.S. FDA-approved label.
Fentanyl is recorded in the NepalDoc medicine catalog for: Pain, Cancer pain, Anesthesia, Analgesia, Breakthrough pain.
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.
