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Gefitinib

Tyrosine kinase inhibitor
Tablet250 mg55 brands · 53 makers
Gefitinib is a tyrosine kinase inhibitor. Gefitinib tablets are indicated for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) substitution mutations as detected by an FDA-approved test. Gefitinib is listed in Nepal's National List of Essential Medicines (NLEM, Sixth Revision 2021) under Immunomodulators, Antineoplastic and Medicines used in Palliative Care.
Generic namegefitinib
Therapeutic classImmunomodulators, Antineoplastic and Medicines used in Palliative Care > 8.2.2 Targeted therapies (complementary list)
Form & strength (NLEM)Tablet: 250 mg
Source / स्रोतNational List of Essential Medicines Nepal (2021); NepalDoc medicine catalog

What it's for

Gefitinib tablets are indicated for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) substitution mutations as detected by an FDA-approved test.

From the U.S. FDA-approved label for Gefitinib. Full label: DailyMed.

Gefitinib tablets are indicated for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) substitution mutations as detected by an FDA-approved test. Limitation of Use: Safety and efficacy of gefitinib tablets have not been established in patients with metastatic NSCLC whose tumors have EGFR mutations other than exon 19 deletions or exon 21 (L858R) substitution mutations.

From the U.S. FDA-approved label for Gefitinib. Full label: DailyMed.

Recommended dose is 250 mg orally, once daily with or without food. 2.1 Patient Selection Select patients for the first-line treatment of metastatic NSCLC with gefitinib tablets based on the presence of EGFR exon 19 deletions or exon 21 L858R mutations in their tumor or plasma specimens. If these mutations are not detected in a plasma specimen, test tumor tissue if feasible.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Interstitial lung disease (ILD): ILD occurred in patients taking gefitinib tablets. Withhold gefitinib tablets for worsening of respiratory symptoms. Discontinue gefitinib tablets if ILD is confirmed.,Hepatotoxicity: Obtain periodic liver function testing. Withhold gefitinib tablets for Grade 2 or higher for ALT and/or AST elevations.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

The following adverse drug reactions are discussed in more detail in other sections of the labeling: Interstitial Lung Disease, Hepatotoxicity, Gastrointestinal Perforation, Severe or Persistent Diarrhea, Ocular Disorders including Keratitis, Bullous and Exfoliative Skin Disorders The most commonly reported adverse drug reactions (ADRs), reported in more than 20% of the patients and greater than placebo were skin reactions…

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

55 products from 53 makers in the NepalDoc medicine catalog use this generic:

BrandCompositionMakerPack
Geftilon 250mg TabletGefitinib (250mg)Celon Lab
Geftinat 250 250mg TabletGefitinib (250mg)Natco Pharma
GEFTINIB 250MG TabletGefitinib (250MG)DABUR INDIA LTD.
GENTILON 250MG TabletGefitinib (250MG)Celon Lab
Kabigef 250 250mg TabletGefitinib (250mg)Fresenius Kabi pharmaceuticals
Acogenib 250mg TabletGefitinib (250mg)Accord Pharmaceuticalsbottle of 30 tablets
Adgef 250 TabletGefitinib (250mg)Adley Formulationsbottle of 15 tablets
Bingeff 250 TabletGefitinib (250mg)Cytogen Pharmaceuticals India Pvt Ltdstrip of 10 tablets
Chemofit 250mg TabletGefitinib (250mg)RPG Life Sciences Ltdstrip of 1 Tablet
Chemogef 250mg TabletGefitinib (250mg)Neon Laboratories Ltdstrip of 10 tablets
Chemoressa 250mg TabletGefitinib (250mg)Biochem Pharmaceutical Industriesstrip of 10 tablets
Denrit 250mg TabletGefitinib (250mg)Pfizer Ltdstrip of 10 tablets
Emfib 250mg TabletGefitinib (250mg)Emcure Pharmaceuticals Ltdstrip of 10 tablets
Fitnib 250mg TabletGefitinib (250mg)Zen Pharma Pvt Ltdstrip of 10 tablets
G-Nib 250mg TabletGefitinib (250mg)BDR Pharmaceuticals Internationals Pvtstrip of 10 tablets
Gefcy 250 TabletGefitinib (250mg)Cyno Pharmaceuticals Ltdstrip of 10 tablets
Geffon TabletGefitinib (250mg)Zydus Cadilastrip of 10 tablets
Geffy 250mg TabletGefitinib (250mg)Intas Pharmaceuticals Ltdstrip of 10 tablets
Geficad TabletGefitinib (250mg)Cadila Pharmaceuticals Ltdstrip of 10 tablets
Gefifect 250mg TabletGefitinib (250mg)Aureate Healthcare Pvt Ltdbottle of 30 tablets
Gefimipsa 250mg CapsuleGefitinib (250mg)Ark Life Sciences Pvt Ltdstrip of 30 capsules
Gefires 250mg TabletGefitinib (250mg)Resonance Laboratories Pvt Ltdstrip of 3 tablets
Gefitec 250mg TabletGefitinib (250mg)United Biotech Pvt Ltdstrip of 10 tablets
Gefitero TabletGefitinib (250mg)Hetero Drugs Ltdstrip of 10 tablets
Gefnab 250mg TabletGefitinib (250mg)Axiommax Oncology Pvt Ltdstrip of 10 tablets
Gefonib 250mg TabletGefitinib (250mg)Miracalus Pharma Pvt Ltdstrip of 10 tablets
Gefshil 250mg TabletGefitinib (250mg)Shilpa Medicare Ltdstrip of 10 tablets
Geftib TabletGefitinib (250mg)Glenmark Pharmaceuticals Ltdstrip of 30 tablets
Gefticip TabletGefitinib (250mg)Cipla Ltdstrip of 30 tablets
Geftifos 250mg TabletGefitinib (250mg)Torrent Pharmaceuticals Ltdstrip of 10 tablets

Showing 30 of 55 catalog products. Search the full catalog in the app.

Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Store at controlled room temperature 20°C-25°C (68°F-77°F).

Storage information from the U.S. FDA-approved label.

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+ Safety information

This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.

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Medicine information only — not medical advice. Confirm with a pharmacist or doctor.