Lisinopril

Hypertension: Initial adult dose is 10 mg once daily. Titrate up to 40 mg daily based on blood pressure response. Initiate patients on diuretics at 5 mg once daily Pediatric patients with glomerular filtration rate > 30 mL/min/1.73m 2: Initial dose in patients 6 years of age and older is 0.07 mg per kg (up to 5 mg total) once daily Heart Failure: Initiate with 5 mg once daily.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Angioedema or a history of hereditary or idiopathic angioedema Hypersensitivity Co-administration of aliskiren with lisinopril in patients with diabetes Lisinopril is contraindicated in combination with a neprilysin inhibitor (e.g., sacubitril). Do not administer Lisinopril tablet USP within 36 hours of switching to or from sacubitril/valsartan, a neprilysin inhibitor.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Angioedema: Discontinue lisinopril, provide appropriate therapy and monitor until resolved Renal impairment: Monitor renal function periodically Hypotension: Patients with other heart or renal diseases have increased risk, monitor blood pressure after initiation Hyperkalemia: Monitor serum potassium periodically Cholestatic jaundice and hepatic failure: Monitor for jaundice or signs of liver failure 5.1 Fetal Toxicity Lisinopril can cause fetal harm when administered to a pregnant woman.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

Common adverse reactions (events 2% greater than placebo) by use: Hypertension: headache, dizziness and cough Heart Failure: hypotension and chest pain Acute Myocardial Infarction: hypotension To report SUSPECTED ADVERSE REACTIONS, contact Lupin Pharmaceuticals, Inc. at 1-800-399-2561 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

115 products from 52 makers in the NepalDoc medicine catalog use this generic:

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Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Store at controlled room temperature, 20° to 25°C (68° to 77°F). Protect from moisture, freezing and excessive heat.

Storage information from the U.S. FDA-approved label.