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Mannitol

Sugar alcohol
Solution7 brands · 7 makers
Mannitol is a sugar alcohol used for the assessment of bronchial hyperresponsiveness in adult and pediatric patients 6 years of age or older who do not have clinically apparent asthma. Mannitol is listed in Nepal's National List of Essential Medicines (NLEM, Sixth Revision 2021) under Diuretics.
Generic namemannitol
Therapeutic classDiuretics
Form & strength (NLEM)Injectable solution: 10%, 20%
Source / स्रोतNational List of Essential Medicines Nepal (2021); NepalDoc medicine catalog

What it's for

ARIDOL is indicated for the assessment of bronchial hyperresponsiveness in adult and pediatric patients 6 years of age or older who do not have clinically apparent asthma.

From the U.S. FDA-approved label for Mannitol. Full label: DailyMed.

ARIDOL is indicated for the assessment of bronchial hyperresponsiveness in adult and pediatric patients 6 years of age or older who do not have clinically apparent asthma.

From the U.S. FDA-approved label for Mannitol. Full label: DailyMed.

For Oral Inhalation Use Only One ARIDOL test kit contains dry powder mannitol capsules in graduated doses and a single patient use inhaler necessary to perform one bronchial challenge test. The mannitol capsules supplied in the ARIDOL kit are to be used with the single patient use inhaler device. Discard the inhaler after use.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

ARIDOL is contraindicated in: Patients with known hypersensitivity to mannitol or to the gelatin used to make the capsules Patients with conditions that may be compromised by induced bronchospasm or repeated spirometry maneuvers. Some examples include: aortic or cerebral aneurysm, uncontrolled hypertension, recent myocardial infarction or cerebral vascular accident. Known hypersensitivity to mannitol or to the gelatin used to make the capsules Conditions that may be compromised by induced bronchospasm or repeated spirometry maneuvers

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Severe bronchospasm: ARIDOL may cause severe bronchospasm in susceptible patients. Administer by trained professionals under the supervision of a physician. Medications and equipment to treat severe bronchospasm must be present in the testing area. Subjects with co-morbid conditions: Use with caution in patients with conditions that may increase sensitivity to the bronchoconstricting or other potential effects of ARIDOL such as: severe cough, ventilatory impairment, unstable angina, or active upper or lower respiratory tract infection that may worsen with use of a bronchial irritant.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

The following clinically significant adverse reaction is described elsewhere in the labeling: Severe Bronchospasm. Most common adverse reactions (rate ≥1%) were headache, pharyngolaryngeal pain, throat irritation, nausea, cough, rhinorrhea, dyspnea, chest discomfort, wheezing, retching and dizziness. To report SUSPECTED ADVERSE REACTIONS, contact Methapharm, Inc.

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

7 products from 7 makers in the NepalDoc medicine catalog use this generic:

BrandCompositionMakerPack
Axatol 20IU InfusionMannitol (20IU)AXA Parenterals Ltdbottle of 100 ml Infusion
Fabitol 20% InfusionMannitol (20% w/v)Elkos Healthcare Pvt Ltdbottle of 100 ml Infusion
Manilup 20% InfusionMannitol (20% w/v)Lupin Ltdbottle of 100 ml Infusion
Manitol 20% InfusionMannitol (20% w/v)Otsuka Pharmaceutical India Pvt Ltdbottle of 350 ml Infusion
Mannitol 20% InfusionMannitol (20% w/v)Albert David Ltdbottle of 350 ml Infusion
Mannitol IP 20% InfusionMannitol (20% w/v)Baxter India Pvt Ltdbottle of 350 ml Infusion
Manogyl 10% InfusionMannitol (10% w/v)J B Chemicals and Pharmaceuticals Ltdbottle of 100 ml Infusion

Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Storage Store below 77°F (25°C) with excursions permitted between 59°F-86°F (15°C-30°C)..

Storage information from the U.S. FDA-approved label.

Medicines for the same conditions

Mannitol is recorded in the NepalDoc medicine catalog for: Chronic bronchitis, Cerebral oedema, Oliguric phase of renal failure, Raised intracranial pressure, Renal function testing, Transurethral prostatic resection.

For Chronic bronchitis: Levofloxacin.

For Cerebral oedema: Dexamethasone.

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+ Safety information

This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.

NepalDoc — Nepal's Healthcare Super-App (Beta) / नेपालको स्वास्थ्य सुपर-एप (बेटा).
Medicine information only — not medical advice. Confirm with a pharmacist or doctor.