INDICATIONS AND USAGE Mesna injection is indicated as a prophylactic agent in reducing the incidence of ifosfamide-induced hemorrhagic cystitis.
From the U.S. FDA-approved label for Mesna. Full label: DailyMed.
INDICATIONS AND USAGE Mesna injection is indicated as a prophylactic agent in reducing the incidence of ifosfamide-induced hemorrhagic cystitis.
From the U.S. FDA-approved label for Mesna. Full label: DailyMed.
DOSAGE AND ADMINISTRATION Mesna injection may be given on a fractionated dosing schedule of three bolus intravenous injections or a single bolus injection followed by two oral administrations of MESNEX tablets as outlined below. The dosing schedule should be repeated on each day that ifosfamide is administered. When the dosage of ifosfamide is adjusted, the ratio of mesna to ifosfamide should be maintained.
Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.
CONTRAINDICATIONS Mesna injection is contraindicated in patients known to be hypersensitive to mesna or to any of the excipients. Known hypersensitivity to mesna or to any of the excipients in mesna injection, including benzyl alcohol.
Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.
WARNINGS AND PRECAUTIONS Hypersensitivity reactions: Anaphylactic reactions have been reported. Less severe hypersensitivity reactions may also occur. Monitor patients. If a reaction occurs, discontinue mesna injection and provide supportive care. Dermatologic toxicity: Skin rash with eosinophilia and systemic symptoms, Stevens-Johnson syndrome, and toxic epidermal necrolysis have occurred. Skin rash, urticaria, and angioedema have also been seen. Monitor patients. If a reaction occurs, discontinue mesna injection and provide supportive care.
Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.
6. ADVERSE REACTIONS The following are discussed in more detail in other sections of the labeling. Hypersensitivity Reactions Dermatological Toxicity Benzyl Alcohol Toxicity Laboratory Test Interferences Use in Patients with a History of Adverse Reactions to Thiol Compounds The most common adverse reactions (> 10%) when mesna injection is given with ifosfamide are nausea, vomiting, constipation, leukopenia, fatigue, fever,…
Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.
5 products from 4 makers in the NepalDoc medicine catalog use this generic:
| Brand | Composition | Maker | Pack |
|---|---|---|---|
| Mesbro 600mg Injection | Mesna (600mg) | Sparsh Remedies Pvt Ltd | ampoule of 3 ml Injection |
| Mesolit Injection | Mesna (200mg) | Neon Laboratories Ltd | vial of 3 ml Injection |
| Mistabron 200mg Respirator Solution | Mesna (200mg) | Dr Reddy's Laboratories Ltd | vial of 3 ml Respules |
| Mistabron 600mg Respirator Solution | Mesna (600mg) | Dr Reddy's Laboratories Ltd | vial of 3 ml Respules |
| Uromitexan 200mg Injection | Mesna (200mg) | Zydus Cadila | vial of 2 ml Injection |
Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.
Store at 20° to 25°C (68° to 77°F), excursions permitted to 15° to 30°C (59° to 86°F) If mesna injection is co-administered with ifosfamide, refer to the ifosfamide prescribing information for safe handling instructions.
Storage information from the U.S. FDA-approved label.
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.
