Methotrexate Injection is a folate analog metabolic inhibitor indicated for: The following neoplastic diseases for the: o Treatment of adult and pediatric patients with acute lymphoblastic leukemia as part of a combination chemotherapy regimen. o Prophylaxis and treatment of adult and pediatric patients with meningeal leukemia.
From the U.S. FDA-approved label for Methotrexate. Full label: DailyMed.
Methotrexate Injection is a folate analog metabolic inhibitor indicated for: The following neoplastic diseases for the: o Treatment of adult and pediatric patients with acute lymphoblastic leukemia as part of a combination chemotherapy regimen. o Prophylaxis and treatment of adult and pediatric patients with meningeal leukemia. o Treatment of adult and pediatric patients with osteosarcoma as part of a combination chemotherapy regimen. o Treatment of adults with squamous cell carcinoma of the head and neck as a single agent.
From the U.S. FDA-approved label for Methotrexate. Full label: DailyMed.
Verify pregnancy status in females of reproductive potential before starting Methotrexate Injection., Neoplastic diseases: Refer to the prescribing information for disease specific dosing recommendations.
Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.
Methotrexate Injection is contraindicated in: Patients with history of severe hypersensitivity to methotrexate., Pregnancy in patients with non-neoplastic diseases., History of severe hypersensitivity to methotrexate., Pregnancy: in patients with non-neoplastic diseases.
Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.
Secondary malignancies can occur., Tumor lysis syndrome can occur in patients with rapidly growing tumors., Immunizations and Risks associated with Live Vaccines: Immunizations may be ineffective. Live vaccines are not recommended due to risk of disseminated infection., Infertility: Can cause impairment of fertility, oligospermia, and menstrual dysfunction. 5.1 Embryo-Fetal Toxicity Based on published reports and its mechanism of action, methotrexate can cause embryo-fetal toxicity, including fetal death when administered to a pregnant woman.
Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.
The following adverse reactions are described, or described in greater detail, in other sections: Hypersensitivity Reactions, Myelosuppression, Serious Infections, Renal Toxicity, Hepatotoxicity, Neurotoxicity, Gastrointestinal Toxicity, Pulmonary Toxicity, Dermatologic Reactions, Secondary Malignancies, Tumor Lysis Syndrome, Increased Risk of Adverse Reactions due to Third-Space Accumulation Common adverse reactions include…
Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.
180 products from 68 makers in the NepalDoc medicine catalog use this generic:
| Brand | Composition | Maker | Pack |
|---|---|---|---|
| Biotrexate 2.5mg Tablet | Methotrexate (2.5mg) | Biochem Pharmaceuticals Industries Limited. | |
| C-Methocel 50mg Injection | Methotrexate (50mg) | Celon Lab | |
| Imutrex 10mg Tablet | Methotrexate (10mg) | Cipla Ltd. | |
| Imutrex 2.5mg Tablet | Methotrexate (2.5mg) | Cipla Ltd. | |
| Imutrex 30mg Injection | Methotrexate (30mg) | Cipla Ltd. | |
| Imutrex 7.5mg Tablet | Methotrexate (7.5mg) | Cipla Ltd. | |
| Oncotrex 10mg Tablet | Methotrexate (10mg) | Sun Pharmaceutical Industries Ltd. | |
| Oncotrex 2.5mg Tablet | Methotrexate (2.5mg) | Sun Pharmaceutical Industries Ltd. | |
| Oncotrex 5mg Tablet | Methotrexate (5mg) | Sun Pharmaceutical Industries Ltd. | |
| Oncotrex 7.5mg Tablet | Methotrexate (7.5mg) | Sun Pharmaceutical Industries Ltd. | |
| Unitrexate 500/20ML Injection | Methotrexate (500/20ML) | United Biotech | |
| UNITREXATE 50mg Injection | Methotrexate (50mg) | United Biotech | |
| Zexate 15mg Injection | Methotrexate (15mg) | Fresenius Kabi pharmaceuticals | |
| Zexate 2.5mg Tablet | Methotrexate (2.5mg) | Fresenius Kabi pharmaceuticals | |
| Zexate 500mg Injection | Methotrexate (500mg) | Fresenius Kabi pharmaceuticals | |
| Zexate 50mg Injection | Methotrexate (50mg) | Fresenius Kabi pharmaceuticals | |
| Aiitrex 25mg Tablet | Methotrexate (25mg) | Naprod Life Sciences | strip of 10 tablets |
| Alltrex 2.5mg Tablet | Methotrexate (2.5mg) | Miracalus Pharma Pvt Ltd | strip of 10 tablets |
| Alltrex 50mg Injection | Methotrexate (50mg) | Miracalus Pharma Pvt Ltd | vial of 2 ml Injection |
| B Trax 1000mg Injection | Methotrexate (1000mg) | Health Biotech Limited | vial of 10 ml Injection |
| Beltrax 5mg Tablet | Methotrexate (5mg) | Blubell Pharma | strip of 10 tablets |
| Biotrexate 1000mg Injection | Methotrexate (1000mg) | Biochem Pharmaceutical Industries | vial of 1 Injection |
| Biotrexate 15mg Injection | Methotrexate (15mg) | Biochem Pharmaceutical Industries | vial of 1 Injection |
| Biotrexate 500mg Injection | Methotrexate (500mg) | Biochem Pharmaceutical Industries | vial of 1 Injection |
| Biotrexate 50mg Injection | Methotrexate (50mg) | Biochem Pharmaceutical Industries | vial of 2 ml Injection |
| Caditrex 50mg Injection | Methotrexate (50mg) | Cadila Pharmaceuticals Ltd | vial of 1 Injection |
| Cytotrex 2.5mg Tablet | Methotrexate (2.5mg) | BDH Industries Ltd | strip of 10 tablets |
| DavaIndia Methotrexate 5mg Tablet | Methotrexate (5mg) | Davaindia Generic Pharmacy | strip of 10 tablets |
| DavaIndia Methotrexate 7.5mg Tablet | Methotrexate (7.5mg) | Davaindia Generic Pharmacy | strip of 10 tablets |
| Dermatrax 7.5mg Tablet | Methotrexate (7.5mg) | Galcare Pharmaceutical Pvt Ltd | strip of 10 tablets |
Showing 30 of 180 catalog products. Search the full catalog in the app.
Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.
Store at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F). Protect from light. After first puncture, store multiple-dose vials at 2°C to 8°C, and use within 30 days. Methotrexate Injection is a hazardous drug. Follow applicable special handling and disposal procedures.
Storage information from the U.S. FDA-approved label.
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.