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Methylprednisolone

Immunomodulators, Antineoplastic and Medicines used in Palliative Care
Injection40 mg · 1 ml · 80 mg1230 brands · 589 makers
Methylprednisolone is listed in Nepal's National List of Essential Medicines (NLEM, Sixth Revision 2021) under Immunomodulators, Antineoplastic and Medicines used in Palliative Care. 1230 brand names for this medicine are listed in the NepalDoc medicine catalog.
Generic namemethylprednisolone
Therapeutic classImmunomodulators, Antineoplastic and Medicines used in Palliative Care > 8.2.4 Hormones and antihormones (complementary list)
Form & strength (NLEM)Injection: 40 mg (as sodium succinate)/ ml in 1 ml single vial; 80 mg (as sodium succinate)/ ml in 1 ml single dose vial
Source / स्रोतNational List of Essential Medicines Nepal (2021); NepalDoc medicine catalog

What it's for

When oral therapy is not feasible, and the strength, dosage form, and route of administration of the drug reasonably lend the preparation to the treatment of the condition, the intravenous or intramuscular use of Methylprednisolone Sodium Succinate for Injection is indicated as follows: Allergic states Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment in asthma, atopic dermatitis, contact dermatitis, drug hypersensitivity reactions, serum sickness, transfusion reactions.

From the U.S. FDA-approved label for Methylprednisolone. Full label: DailyMed.

When oral therapy is not feasible, and the strength, dosage form, and route of administration of the drug reasonably lend the preparation to the treatment of the condition, the intravenous or intramuscular use of Methylprednisolone Sodium Succinate for Injection is indicated as follows: Allergic states Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment in asthma, atopic dermatitis, contact dermatitis, drug hypersensitivity reactions, serum sickness, transfusion reactions. Dermatologic diseases Bullous dermatitis herpetiformis, exfoliative erythroderma, mycosis fungoides, pemphigus, severe erythema multiforme (Stevens-Johnson syndrome). Endocrine disorders Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the drug of choice; synthetic analogs may be used in conjunction with mineralocorticoids where applicable; in infancy, mineralocorticoid supplementation is of particular importance), congenital adrenal hyperplasia, hypercalcemia associated with cancer, nonsuppurative thyroiditis. Gastrointestinal diseases To tide the patient over a critical period of the disease in regional enteritis (systemic therapy) and ulcerative colitis.

From the U.S. FDA-approved label for Methylprednisolone. Full label: DailyMed.

Use only Water for Injection or Bacteriostatic Water For Injection with Benzyl Alcohol when reconstituting methylprednisolone sodium succinate (see DESCRIPTION ). Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. This preparation may be administered by intravenous injection, by intravenous infusion, or by intramuscular injection, the preferred method for initial emergency use being intravenous injection.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Methylprednisolone Sodium Succinate Sterile Powder is contraindicated: in systemic fungal infections and patients with known hypersensitivity to the product and its constituents; The methylprednisolone sodium succinate for injection 40 mg presentation includes lactose monohydrate produced from cow’s milk. This presentation is therefore contraindicated in patients with a known or suspected hypersensitivity to cow’s milk or its components or other dairy products because it may contain trace amounts of milk ingredients. for intrathecal administration.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Serious Neurologic Adverse Reactions with Epidural Administration Serious neurologic events, some resulting in death, have been reported with epidural injection of corticosteroids. Specific events reported include, but are not limited to, spinal cord infarction, paraplegia, quadriplegia, cortical blindness, and stroke. These serious neurologic events have been reported with and without use of fluoroscopy. The safety and effectiveness of epidural administration of corticosteroids have not been established, and corticosteroids are not approved for this use.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

The following adverse reactions have been reported with methylprednisolone sodium succinate or other corticosteroids: Allergic reactions: Allergic or hypersensitivity reactions, anaphylactoid reaction, anaphylaxis, angioedema. Blood and lymphatic system disorders: Leukocytosis.

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

1230 products from 589 makers in the NepalDoc medicine catalog use this generic:

BrandCompositionMakerPack
Depo Medrol 40mg/ml InjectionMethylprednisolone (40mg/ml)Pfizer Ltd.
Depo Medrol 80mg/ml InjectionMethylprednisolone (80mg/ml)Pfizer Ltd.
Depopred 40mg InjectionMethylprednisolone (40mg)Sun Pharmaceutical Industries Ltd.
Depopred 80mg InjectionMethylprednisolone (80mg)Sun Pharmaceutical Industries Ltd.
Ivepred 1000mg InjectionMethylprednisolone (1000mg)Sun Pharmaceutical Industries Ltd.
Medrol 16 16mg TabletMethylprednisolone (16mg)Pfizer Ltd.
Medrol 4 4mg TabletMethylprednisolone (4mg)Pfizer Ltd.
Medrol 8mg TabletMethylprednisolone (8mg)Pfizer Ltd.
Methapred 16mg TabletMethylprednisolone (16mg)Omnica Laboratories Pvt. Ltd..
Methapred 2mg TabletMethylprednisolone (2mg)Omnica Laboratories Pvt. Ltd..
Methapred 32 mg TabletMethylprednisolone (32 mg)Omnica Laboratories Pvt. Ltd..
Methapred 4mg TabletMethylprednisolone (4mg)Omnica Laboratories Pvt. Ltd..
Methapred 8mg TabletMethylprednisolone (8mg)Omnica Laboratories Pvt. Ltd..
Methpred 500 mg, 1 mg InjectionMethylprednisolone (500 mg, 1 mg)Troikaa Pharmaceuticals Ltd.
Aarpred 4mg TabletMethylprednisolone (4mg)Dial Pharmaceuticals Pvt Ltdstrip of 10 tablets
Abimeth 16 TabletMethylprednisolone (16mg)Abigail Care Pharmaceuticalstrip of 10 tablets
Abimeth 8 TabletMethylprednisolone (8mg)Abigail Care Pharmaceuticalstrip of 10 tablets
Accmethyl 4 TabletMethylprednisolone (4mg)Accilex Nutricorpstrip of 10 tablets
Accmethyl 8mg TabletMethylprednisolone (8mg)Accilex Nutricorpstrip of 10 tablets
Accmethyl A 80mg InjectionMethylprednisolone (80mg)Accilex Nutricorpvial of 2 ml Injection
Acepred 4 TabletMethylprednisolone (4mg)Acekinetics Healthcare Pvt Ltdstrip of 10 tablets
Acepred 8mg TabletMethylprednisolone (8mg)Acekinetics Healthcare Pvt Ltdstrip of 10 tablets
Aconpride 4mg TabletMethylprednisolone (4mg)Aconwell Pharma Pvt Ltdstrip of 10 tablets
Aconpride 8mg TabletMethylprednisolone (8mg)Aconwell Pharma Pvt Ltdstrip of 10 tablets
Actdrol 1000mg InjectionMethylprednisolone (1000mg)Burgeon Health Series Private Limitedvial of 1 Injection
Actdrol 125mg InjectionMethylprednisolone (125mg)Burgeon Health Series Private Limitedvial of 1 Injection
Actdrol 40mg InjectionMethylprednisolone (40mg)Burgeon Health Series Private Limitedvial of 1 Injection
Actdrol 500mg InjectionMethylprednisolone (500mg)Burgeon Health Series Private Limitedvial of 1 Injection
Actipred 4mg TabletMethylprednisolone (4mg)UHC Life Sciencesstrip of 10 tablets
Acto Pred 16mg TabletMethylprednisolone (16mg)Ferring Pharmaceuticalsstrip of 10 tablets

Showing 30 of 1230 catalog products. Search the full catalog in the app.

Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

CONDITIONS Protect from light. Store unreconstituted product at controlled room temperature 20° to 25°C (68° to 77°F). Store reconstituted solution (not further diluted) at controlled room temperature 20° to 25°C (68° to 77°F), and use it within 48 hours. See section DOSAGE AND ADMINISTRATION, for storage of further diluted solution.

Storage information from the U.S. FDA-approved label.

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+ Safety information

This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.

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Medicine information only — not medical advice. Confirm with a pharmacist or doctor.