Nitrofurantoin

2 DOSAGE & ADMINISTRATION Adult Patients: 50 mg to 100 mg four times a day -the lower dosage level is recommended for uncomplicated urinary tract infections. Pediatric Patients: 5 mg/kg to 7 mg/kg of body weight per 24 hours, given in four divided doses (contraindicated under one month of age). 2.1 Recommended Dosage and Administration in Adult Patients The recommended dosage is 50 mg to 100 mg of nitrofurantoin four times a day.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Nitrofurantoin is contraindicated in: patients with known hypersensitivity to nitrofurantoin. patients with a previous history of cholestatic jaundice/hepatic dysfunction associated with nitrofurantoin. patients who have anuria, oliguria, or significant impairment of renal function (creatinine clearance under 60 mL per minute or clinically significant elevated serum creatinine) due to an increased risk of toxicity resulting from impaired excretion of the drug.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving nitrofurantoin. If signs and symptoms of a hypersensitivity reaction occurs, immediately discontinue nitrofurantoin. Pulmonary Reactions: Discontinue if sign and symptoms of pulmonary reactions occur and take appropriate measures. Hepatotoxicity: Discontinue if signs/symptoms of hepatitis occur. Monitor liver function tests. Neuropathy: Peripheral neuropathy has occurred. Hemolytic Anemia: Discontinue if sign and symptoms of hemolysis occur.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

The following clinically significant adverse reactions are discussed in more detail in other sections of the labeling: Hypersensitivity Reactions Pulmonary Reactions Hepatotoxicity Neuropathy Hemolytic anemia Clostridioides difficile -associated Diarrhea Persistence or Reappearance of Bacteriuria The following adverse reactions associated with the use of nitrofurantoin formulations, including nitrofurantoin oral suspension,…

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

140 products from 124 makers in the NepalDoc medicine catalog use this generic:

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Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Stored between 20°C to 25°C (68°F to 77°F); Protect from freezing. Keep out of reach of children.

Storage information from the U.S. FDA-approved label.