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Ondansetron

5-HT 3 receptor antagonist
Injection · Tablet2 mg · 2 ml · 4 ml · 4 mg2408 brands · 1240 makers
Ondansetron is a 5-HT 3 receptor antagonist. Ondansetron oral solution is indicated for the prevention of nausea and vomiting associated with: highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m 2 initial and repeat courses of moderately emetogenic cancer chemotherapy radiotherapy in patients receiving either total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen Ondansetron oral solution is also indicated for the prevention of postoperative nausea and/or vomiting. Ondansetron is listed in Nepal's National List of Essential Medicines (NLEM, Sixth Revision 2021) under Immunomodulators, Antineoplastic and Medicines used in Palliative Care.
Generic nameondansetron
Therapeutic classImmunomodulators, Antineoplastic and Medicines used in Palliative Care > 8.2.5 Supportive medicines (complementary list)
Therapeutic classGastrointestinal Medicines > 17.2 Antiemetic medicines
Form & strength (NLEM)Injection: 2 mg (as hydrochloride)/ ml in 2 ml, 4 ml vial; Oral liquid: 4 mg base/5 ml; Tablet: 2 mg, 4 mg (as hydrochloride); [a] not in infants ≤ 1 month
Form & strength (NLEM)Injection:2 mg (as hydrochloride)/ ml in 2 ml, 4 ml vial; Oral liquid: 4 mg base/5 ml; Tablet: 2 mg, 4 mg (as hydrochloride); [a] not in infants ≤ 1 month
Source / स्रोतNational List of Essential Medicines Nepal (2021); NepalDoc medicine catalog

What it's for

Ondansetron oral solution is indicated for the prevention of nausea and vomiting associated with: highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m 2 initial and repeat courses of moderately emetogenic cancer chemotherapy radiotherapy in patients receiving either total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen Ondansetron oral solution is also indicated for the prevention of postoperative nausea and/or vomiting.

From the U.S. FDA-approved label for Ondansetron. Full label: DailyMed.

Ondansetron oral solution is indicated for the prevention of nausea and vomiting associated with: highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m 2 initial and repeat courses of moderately emetogenic cancer chemotherapy radiotherapy in patients receiving either total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen Ondansetron oral solution is also indicated for the prevention of postoperative nausea and/or vomiting. Ondansetron oral solution is a 5-HT 3 receptor antagonist indicated for the prevention of: nausea and vomiting associated with highly emetogenic cancer chemotherapy, including cisplatin greater than or equal to 50 mg/m 2. nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy. nausea and vomiting associated with radiotherapy in patients receiving either total body irradiation, single high-dose fraction to the abdomen, or daily fractions to the abdomen. postoperative nausea and/or vomiting.

From the U.S. FDA-approved label for Ondansetron. Full label: DailyMed.

See full prescribing information for the recommended dosage in adults and pediatrics. Patients with severe hepatic impairment: do not exceed a total daily dose of 8 mg. 2.1 Dosage The recommended dosage regimens for adult and pediatric patients are described in Table 1 and Table 2, respectively.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Ondansetron is contraindicated in patients: known to have hypersensitivity (e.g., anaphylaxis) to ondansetron or any of the components of the formulation receiving concomitant apomorphine due to the risk of profound hypotension and loss of consciousness Patients known to have hypersensitivity (e.g., anaphylaxis) to ondansetron or any components of the formulation. Concomitant use of apomorphine.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Hypersensitivity Reactions, Including Anaphylaxis and Bronchospasm: Discontinue ondansetron if suspected. Monitor and treat promptly per standard of care until signs and symptoms resolve. QT Interval Prolongation and Torsade de Pointes: Avoid ondansetron in patients with congenital long QT syndrome; monitor with electrocardiograms (ECGs) if concomitant electrolyte abnormalities, cardiac failure or arrhythmias, or use of other QT prolonging drugs. Serotonin Syndrome: Reported with 5-HT 3 receptor antagonists alone but particularly with concomitant use of serotonergic drugs.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

The following clinically significant adverse reactions are described elsewhere in the labeling: Hypersensitivity Reactions QT Prolongation Serotonin Syndrome Myocardial Ischemia Masking of Progressive Ileus and Gastric Distension The most common adverse reactions in adults for the: prevention of chemotherapy-induced (≥ 5%) are: headache, malaise/fatigue, constipation, diarrhea.

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

2408 products from 1240 makers in the NepalDoc medicine catalog use this generic:

BrandCompositionMakerPack
DANTRON 30 mg SyrupOndansetron (30 mg)CTL Pharmaceuticals Pvt. Ltd.
DANTRON 4MG TabletOndansetron (4MG)CTL Pharmaceuticals Pvt. Ltd.
DANTRON 8MG TabletOndansetron (8MG)CTL Pharmaceuticals Pvt. Ltd.
Emeset 4 4mg TabletOndansetron (4mg)Cipla Ltd.
Emeset 8 8mg TabletOndansetron (8mg)Cipla Ltd.
Emigo MD 4mg TabletOndansetron (4mg)Zuventus Healthcare Ltd
Emigo MD 80mg TabletOndansetron (80mg)Nova Genetica Pvt. Ltd.
Nemesis 4mg TabletOndansetron (4mg)Apple International Pharmaceuticals Pvt. Ltd.
Nemesis 8mg TabletOndansetron (8mg)Apple International Pharmaceuticals Pvt. Ltd.
Nuset 8 8mg InjectionOndansetron (8mg)Sun Pharmaceutical Industries Ltd.
Odanse 2mg SyrupOndansetron (2mg)Indchemie Health Specialities Pvt. Ltd.
Odanse 4mg TabletOndansetron (4mg)Indchemie Health Specialities Pvt. Ltd.
ODT 4 mg/ 5 ml SyrupOndansetron (4 mg/ 5 ml)Curex Pharmaceuticals Pvt. Ltd.
ODT 4mg TabletOndansetron (4mg)Curex Pharmaceuticals Pvt. Ltd.
ODT 8 mg TabletOndansetron (8 mg)Curex Pharmaceuticals Pvt. Ltd.
Ofran 8mg TabletOndansetron (8mg)Square Pharmaceuticals Ltd.
Ofran Oral Solution 4 mg/ 5 ml Oral SolutionOndansetron (4 mg/ 5 ml)Square Pharmaceuticals Ltd.
Omitron 2mg, 4ML InjectionOndansetron (2mg, 4ML)National Healthcare Pvt. Ltd.
Onda 4mg TabletOndansetron (4mg)Asian Pharmaceuticals Pvt. Ltd.
Onda SyrupOndansetronAsian Pharmaceuticals Pvt. Ltd.
Ondem 30ml SyrupOndansetron (30ml)Alkem Laboratories Ltd.
Ondem 4gm InjectionOndansetron (4gm)Alkem Laboratories Ltd.
Ondem 4mg TabletOndansetron (4mg)Alkem Laboratories Ltd.
Ondem 8mg TabletOndansetron (8mg)Alkem Laboratories Ltd.
ONDEM 8MG/4ML InjectionOndansetron (8MG/4ML)Alkem Laboratories Ltd.
Ondem MD 4 4mg TabletOndansetron (4mg)Alkem Laboratories Ltd.
ONO 2MG/5ML SyrupOndansetron (2MG/5ML)Lomus Pharmaceutical Pvt. Ltd.
ONO 4MG TabletOndansetron (4MG)Lomus Pharmaceutical Pvt. Ltd.
Onsat 8mg TabletOndansetron (8mg)Beximco Pharmaceuticals Ltd.
Ontron 4 4mg TabletOndansetron (4mg)Amtech Pharma

Showing 30 of 2408 catalog products. Search the full catalog in the app.

Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Protect from light.

Storage information from the U.S. FDA-approved label.

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+ Safety information

This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.

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Medicine information only — not medical advice. Confirm with a pharmacist or doctor.