Orlistat

One 120-mg capsule three times a day with each main meal containing fat (during or up to 1 hour after the meal). Advise patients to take a nutritionally balanced, reduced-calorie diet that contains approximately 30% of calories from fat. Distribute the daily intake of fat, carbohydrate, and protein over three main meals.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

ORLISTAT is contraindicated in: Pregnancy Patients with chronic malabsorption syndrome Patients with cholestasis Patients with known hypersensitivity to ORLISTAT or to any component of this product Pregnancy Chronic malabsorption syndrome Cholestasis Known hypersensitivity to ORLISTAT or to any component of this product

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

ORLISTAT has drug interactions and can decrease vitamin absorption. Take a multivitamin supplement that contains fat-soluble vitamins to ensure adequate nutrition. Rare cases of severe liver injury with hepatocellular necrosis or acute hepatic failure have been reported. Patients may develop oxalate nephrolithiasis and oxalate nephropathy following treatment with ORLISTAT. Monitor renal function in patients at risk for renal insufficiency. Discontinue ORLISTAT if oxalate nephropathy develops. Substantial weight loss can increase the risk of cholelithiasis.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

Most common treatment emergent adverse reactions (≥5% and at least twice that of placebo) include oily spotting, flatus with discharge, fecal urgency, fatty/oily stool, oily evacuation, increased defecation and fecal incontinence. To report SUSPECTED ADVERSE REACTIONS, contact the Safety Call Center at 1-877-778-8969 or FDA at 1‑800‑FDA‑1088 (1-800-332-1088) or www.fda.gov/medwatch.

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

126 products from 83 makers in the NepalDoc medicine catalog use this generic:

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Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Store at 25°C (77°F); excursions permitted to 15° to 30°C (59° to 86°F). Keep bottle tightly closed. ORLISTAT should not be used after the given expiration date.

Storage information from the U.S. FDA-approved label.