Oxaliplatin

Administer oxaliplatin injection 85 mg/m 2 as an intravenous infusion over 120 minutes concurrently with leucovorin over 120 minutes in separate bags, followed by fluorouracil on Day 1 of each 14-day cycle. Administer fluorouracil and leucovorin on Day 2 as recommended., Adjuvant Treatment: Continue treatment for up to 12 cycles or unacceptable toxicity., Advanced Colorectal Cancer: Continue treatment until disease progression or unacceptable toxicity.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Oxaliplatin is contraindicated in patients with a history of a hypersensitivity reaction to oxaliplatin or other platinum-based drugs. Reactions have included anaphylaxis., History of hypersensitivity reaction to oxaliplatin or other platinum-based drugs.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Peripheral Sensory Neuropathy: Acute and delayed neuropathy can occur. Avoid topical application of ice. Reduce the dose or permanently discontinue oxaliplatin as recommended., Severe Myelosuppression: Delay oxaliplatin until neutrophils are greater than or equal to 1.5 x 10 9 /L and platelets are greater than or equal to 75 x 10 9 /L. Withhold oxaliplatin for sepsis or septic shock.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

The following clinically significant adverse reactions are described elsewhere in labeling: Hypersensitivity Reactions, Peripheral Sensory Neuropathy, Severe Myelosuppression, Reversible Posterior Leukoencephalopathy Syndrome, Pulmonary Toxicity, Hepatotoxicity, QT Interval Prolongation and Ventricular Arrhythmias, Rhabdomyolysis, Hemorrhage Most common adverse reactions (incidence greater than or equal to 40%) were…

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

97 products from 52 makers in the NepalDoc medicine catalog use this generic:

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Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Store at 25°C (77°F); Protect from light (keep in original outer carton).

Storage information from the U.S. FDA-approved label.