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Pethidine

Medicines for Pain and Palliative Care
Injection50 mg · 1 ml2 brands · 2 makers
Pethidine is listed in Nepal's National List of Essential Medicines (NLEM, Sixth Revision 2021) under Medicines for Pain and Palliative Care. According to its FDA label, it is used for the management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. 2 brand names for this medicine are listed in the NepalDoc medicine catalog.
Generic namepethidine
Therapeutic classMedicines for Pain and Palliative Care > 2.2 Opioid analgesics
Form & strength (NLEM)Injection: 50 mg (hydrochloride) in 1 ml ampoule
Source / स्रोतNational List of Essential Medicines Nepal (2021); NepalDoc medicine catalog

What it's for

Meperidine Hydrochloride Tablets and Oral Solution are indicated for the management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.

From the U.S. FDA-approved label for Pethidine. Full label: DailyMed.

Meperidine Hydrochloride Tablets and Oral Solution are indicated for the management of acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.

From the U.S. FDA-approved label for Pethidine. Full label: DailyMed.

Meperidine Hydrochloride Tablets and Oral Solution should be prescribed only by healthcare professionals who are knowledgeable about the use of opioids and how to mitigate the associated risks., Use the lowest effective dosage for the shortest duration of time consistent with individual patient treatment goals.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Meperidine Hydrochloride Tablets and Oral Solution are contraindicated in patients with: Significant respiratory depression, Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment, Concomitant use of monoamine oxidase inhibitors (MAOIs) or within 14 days of having taken an MAOI, Known or suspected gastrointestinal obstruction, including paralytic ileus, Hypersensitivity to meperidine or to any of the other ingredients of the product (e.g., anaphylaxis), Significant respiratory depression.…

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Opioid-Induced Hyperalgesia and Allodynia: Opioid-Induced Hyperalgesia (OIH) occurs when an opioid analgesic paradoxically causes an increase in pain, or an increase in sensitivity to pain. If OIH is suspected, carefully consider appropriately decreasing the dose of the current opioid analgesic, or opioid rotation., Serotonin Syndrome: Potentially life-threatening condition could result from concomitant serotonergic drug administration.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

The following serious adverse reactions are described, or described in greater detail, in other sections: Addiction, Abuse, and Misuse, Life-Threatening Respiratory Depression, Interactions with Benzodiazepines or Other CNS Depressants, Neonatal Opioid Withdrawal Syndrome, Opioid-Induced Hyperalgesia and Allodynia, Serotonin Syndrome, Adrenal Insufficiency, Severe Hypotension, Gastrointestinal Adverse Reactions, Seizures,…

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

2 products from 2 makers in the NepalDoc medicine catalog use this generic:

BrandCompositionMakerPack
Pethitroy 50mg InjectionPethidine (50mg)Troikaa Pharmaceuticals Ltdvial of 1 ml Injection
Verpat 50mg InjectionPethidine (50mg)Verve Healthcare Ltdampoule of 1 ml Injection

Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Medicines for the same conditions

Pethidine is recorded in the NepalDoc medicine catalog for: Anaesthesia, Postoperative pain, Moderate to severe acute pain, Obstetric analgesia.

For Postoperative pain: Mefenamic acid.

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+ Safety information

This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.

NepalDoc — Nepal's Healthcare Super-App (Beta) / नेपालको स्वास्थ्य सुपर-एप (बेटा).
Medicine information only — not medical advice. Confirm with a pharmacist or doctor.