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Pilocarpine

Muscarinic cholinergic agonist
Solution · Drops15 brands · 11 makers
Pilocarpine is a muscarinic cholinergic agonist. Pilocarpine hydrochloride ophthalmic solution is indicated for the: Pilocarpine hydrochloride ophthalmic solution is a muscarinic cholinergic agonist indicated for: The reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. Pilocarpine is listed in Nepal's National List of Essential Medicines (NLEM, Sixth Revision 2021) under Ophthalmological Preparations.
Generic namepilocarpine
Therapeutic classOphthalmological Preparations > 21.4 Miotics and antiglaucoma medicines
Form & strength (NLEM)Solution (eye drops): 2%, 4% (hydrochloride)
Source / स्रोतNational List of Essential Medicines Nepal (2021); NepalDoc medicine catalog

What it's for

Pilocarpine hydrochloride ophthalmic solution is indicated for the: Pilocarpine hydrochloride ophthalmic solution is a muscarinic cholinergic agonist indicated for: The reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. The management of acute angle-closure glaucoma.

From the U.S. FDA-approved label for Pilocarpine. Full label: DailyMed.

Pilocarpine hydrochloride ophthalmic solution is indicated for the: Pilocarpine hydrochloride ophthalmic solution is a muscarinic cholinergic agonist indicated for: The reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. The management of acute angle-closure glaucoma. The prevention of postoperative elevated IOP associated with laser surgery. The induction of miosis. 1.1 Reduction of Elevated Intraocular Pressure (IOP) in Patients with Open-Angle Glaucoma or Ocular Hypertension 1.2 Management of Acute Angle-Closure Glaucoma 1.3 Prevention of Postoperative Elevated IOP Associated with Laser Surgery 1.4 Induction of Miosis.

From the U.S. FDA-approved label for Pilocarpine. Full label: DailyMed.

Instill one drop in the eye(s) up to four times daily. 2.1 Reduction of Elevated Intraocular Pressure (IOP) in Patients with Open-Angle Glaucoma or Ocular Hypertension One drop of pilocarpine hydrochloride ophthalmic solution 1%, 2% or 4% should be applied topically in the eye(s) up to four times daily. Pilocarpine-naïve patients should be started on the 1% concentration as higher concentrations are often not tolerated initially.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Poor illumination: Exercise caution in night driving and other hazardous occupations in poor illumination. Pre-existing retinal disease: Rare cases of retinal detachment have been reported; a thorough examination of the retina including funduscopy is advised in all patients prior to the initiation of therapy. Iritis: Caution is advised in patients with iritis. Congenital glaucoma: Caution is advised in pediatric patients with primary congenital glaucoma for control of IOP as cases of a paradoxical increase in IOP have been reported.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

Clinical Studies Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

15 products from 11 makers in the NepalDoc medicine catalog use this generic:

BrandCompositionMakerPack
Carpine 0.5% InjectionPilocarpine (0.5%)Intas Pharmaceuticals Ltdvial of 1 ml Injection
Carpine Eye DropPilocarpine (2% w/v)Intas Pharmaceuticals Ltdpacket of 5 ml Eye Drop
Carpinol Eye DropPilocarpine (0.5%)Sunways India Pvt Ltdbottle of 1 ml Eye Drop
Locarp 2% Eye DropPilocarpine (2% w/v)Cadila Pharmaceuticals Ltdpacket of 5 ml Eye Drop
Pilagan Eye DropPilocarpine (2% w/v)Allergan India Pvt Ltdpacket of 5 ml Eye Drop
Pilo 2 Eye DropPilocarpine (2% w/v)Aurolabpacket of 5 ml Eye Drop
Pilocar 1% Eye DropPilocarpine (1%)FDC Ltdpacket of 5 ml Eye Drop
Pilocar 2% Eye DropPilocarpine (2% w/v)FDC Ltdbottle of 5 ml Eye Drop
Pilocar 4% Eye DropPilocarpine (4%)FDC Ltdpacket of 5 ml Eye Drop
Pilocarpin 2% Eye DropPilocarpine (2% w/v)FDC Ltdpacket of 5 ml Eye Drop
Pilodrops 2% Eye DropPilocarpine (2% w/v)Micro Labs Ltdpacket of 5 ml Eye Drop
Pilomax TabletPilocarpine (5mg)Sun Pharmaceutical Industries Ltdstrip of 10 tablets
Pilomin 0.5% InjectionPilocarpine (0.5%)Entod Pharmaceuticals Ltdvial of 1 ml Injection
Pilopress Eye DropPilocarpine (2% w/v)Centaur Pharmaceuticals Pvt Ltdpacket of 5 ml Eye Drop
Pilotbg TabletPilocarpine (5mg)TBG pharma ltdstrip of 10 tablets

Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

STORAGE: Store at 15º to 25°C (59º to 77°F) and protect from freezing.

Storage information from the U.S. FDA-approved label.

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+ Safety information

This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.

NepalDoc — Nepal's Healthcare Super-App (Beta) / नेपालको स्वास्थ्य सुपर-एप (बेटा).
Medicine information only — not medical advice. Confirm with a pharmacist or doctor.