Quinine

Adults (≥ 16 years of age): 648 mg (two capsules) every 8 hours for 7 days. Patients with severe chronic renal impairment: one loading dose of 648 mg (two capsules) followed 12 hours later by 324 mg (one capsule) every 12 hours for 7 days. 2.1 Treatment of Uncomplicated P.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Quinine sulfate is contraindicated in patients with the following: Prolongation of QT interval Glucose-6-phosphate dehydrogenase (G6PD) deficiency Myasthenia gravis Known hypersensitivity to quinine, mefloquine, or quinidine Optic neuritis Quinine sulfate is contraindicated in patients with the following: Prolonged QT interval. One case of a fatal ventricular arrhythmia was reported in an elderly patient with a prolonged QT interval at baseline, who received quinine sulfate intravenously for P.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Not indicated for the prevention or treatment of nocturnal leg cramps. Risk of serious and life-threatening adverse reactions. Thrombocytopenia, including ITP and HUS/TTP, has been reported. Discontinue drug. QT prolongation and ventricular arrhythmias. Avoid concomitant use with drugs known to prolong QT interval. Avoid concomitant use with rifampin. Quinine sulfate treatment failures have been reported. Avoid concomitant use with neuromuscular blocking agents. Quinine sulfate may potentiate neuromuscular blockade and cause respiratory depression. Serious and life threatening hypersensitivity reactions. Discontinue drug.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

Most common adverse reactions are a cluster of symptoms called "cinchonism", which occurs to some degree in almost all patients taking quinine: headache, vasodilation and sweating, nausea, tinnitus, hearing impairment, vertigo or dizziness, blurred vision, disturbance in color perception, vomiting, diarrhea, abdominal pain, deafness, blindness, and disturbances in cardiac rhythm or conduction.

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

195 products from 94 makers in the NepalDoc medicine catalog use this generic:

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Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Storage Store at 25°C (77°F);

Storage information from the U.S. FDA-approved label.