Sevelamer

Starting dose of sevelamer carbonate tablets is 0.8 or 1.6 grams administered orally three times per day with meals based on serum phosphorus levels for adult patients. Titrate by 0.8 g per meal in two week intervals for adult patients as needed to obtain serum phosphorus target. 2.1 General Dosing Information Starting Dose for Adult Patients Not Taking a Phosphate Binder.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Sevelamer carbonate tablets are contraindicated in patients with bowel obstruction. Sevelamer carbonate tablets are contraindicated in patients with known hypersensitivity to sevelamer carbonate, sevelamer hydrochloride, or to any of the excipients. Bowel obstruction. Known hypersensitivity to sevelamer carbonate, sevelamer hydrochloride, or to any of the excipients.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Serious cases of dysphagia, bowel obstruction, and perforation have been associated with sevelamer use, some requiring hospitalization and surgery. 5.1 Gastrointestinal Adverse Events Cases of dysphagia and esophageal tablet retention have been reported in association with use of the tablet formulation of sevelamer, some requiring hospitalization and intervention. Consider using sevelamer suspension in patients with a history of swallowing disorders. Cases of bowel obstruction and perforation have also been reported with sevelamer use.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

Most of the safety experience is with sevelamer tablets and sevelamer hydrochloride. In long-term studies with sevelamer hydrochloride, which contains the same active moiety as sevelamer carbonate, the most common adverse events included: vomiting (22%), nausea (20%), diarrhea (19%), dyspepsia (16%), abdominal pain (9%), flatulence (8%) and constipation (8%).

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

132 products from 71 makers in the NepalDoc medicine catalog use this generic:

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Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Storage: Store at 20° to 25°C (68° to 77°F). Protect from moisture.

Storage information from the U.S. FDA-approved label.