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Sildenafil

Phosphodiesterase-5 (PDE-5) inhibitor
Capsule · Injection · Sachet · Spray0.8mg · 10mg · 20mg · 25mg392 brands · 232 makers
Sildenafil is a phosphodiesterase-5 (PDE-5) inhibitor used for the treatment of pulmonary arterial hypertension (WHO Group I) in adults to improve exercise ability and delay clinical worsening.
Generic namesildenafil
Form & strengthCatalog forms: Capsule, Injection, Sachet, Spray, Suspension, Tablet · Catalog strengths: 0.8mg, 10mg, 20mg, 25mg, 40mg, 50mg, 100mg, 500mg
Source / स्रोतNepalDoc medicine catalog

What it's for

Sildenafil tablets are indicated for the treatment of pulmonary arterial hypertension (WHO Group I) in adults to improve exercise ability and delay clinical worsening. The delay in clinical worsening was demonstrated when sildenafil tablets were added to background epoprostenol therapy.

From the U.S. FDA-approved label for Sildenafil. Full label: DailyMed.

Sildenafil tablets are indicated for the treatment of pulmonary arterial hypertension (WHO Group I) in adults to improve exercise ability and delay clinical worsening. The delay in clinical worsening was demonstrated when sildenafil tablets were added to background epoprostenol therapy. Studies establishing effectiveness were short-term (12 to 16 weeks), and included predominately patients with New York Heart Association (NYHA) Functional Class II-III symptoms and idiopathic etiology (71%) or associated with connective tissue disease (CTD) (25%). Limitation of Use: Adding sildenafil to bosentan therapy does not result in any beneficial effect on exercise capacity.

From the U.S. FDA-approved label for Sildenafil. Full label: DailyMed.

2 DOSAGE & ADMINISTRATION Tablet: 20 mg three times a day, 4-6 hours apart 2.1 Sildenafil Tablets The recommended dose of sildenafil tablets is 20 mg three times a day. Administer sildenafil tablets doses 4-6 hours apart. In the clinical trial no greater efficacy was achieved with the use of higher doses.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Sildenafil tablets are contraindicated in patients with: Concomitant use of organic nitrates in any form, either regularly or intermittently, because of the greater risk of hypotension., Concomitant use of riociguat, a guanylate cyclase stimulator. PDE-5 inhibitors, including sildenafil, may potentiate the hypotensive effects of riociguat., Known hypersensitivity to sildenafil or any component of the tablet.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Increased mortality with increasing doses in pediatric patients. Not recommended for use in pediatric patients., Vasodilation effects may be more common in patients with hypotension or on antihypertensive therapy., Use in pulmonary veno-occlusive disease may cause pulmonary edema and is not recommended., Hearing or visual impairment: Seek medical attention if sudden decrease or loss of vision or hearing occurs., Pulmonary hypertension secondary to sickle cell disease: Sildenafil may cause serious vaso-occlusive crises.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

The following serious adverse events are discussed elsewhere in the labeling: Mortality with pediatric use, Hypotension, Vision loss, Hearing loss, Priapism, Vaso-occlusive crisis Most common adverse reactions greater than or equal to 3% and more frequent than placebo were epistaxis, headache, dyspepsia, flushing, insomnia, erythema, dyspnea, and rhinitis.

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

392 products from 232 makers in the NepalDoc medicine catalog use this generic:

BrandCompositionMakerPack
Alsigra 25 25mg TabletSildenafil (25mg)Alembic Pharmaceuticals Ltd.
Alsigra 50 50mg TabletSildenafil (50mg)Alembic Pharmaceuticals Ltd.
Aryagra 50mg TabletSildenafil (50mg)Arya Pharma Lab Pvt. Ltd.
Caverta 25mg TabletSildenafil (25mg)Sun Pharmaceutical Industries Ltd.
Caverta 50mg TabletSildenafil (50mg)Sun Pharmaceutical Industries Ltd.
Edegra 50mg TabletSildenafil (50mg)Sun Pharmaceutical Industries Ltd.
Giagra 100 100mg TabletSildenafil (100mg)G.D. Laboratories Pvt. Ltd.
Giagra 50 50mg TabletSildenafil (50mg)G.D. Laboratories Pvt. Ltd.
Medigra 25mg TabletSildenafil (25mg)Quest Pharmaceuticals Pvt. Ltd.
Medigra 50mg TabletSildenafil (50mg)Quest Pharmaceuticals Pvt. Ltd.
Penegra 50mg TabletSildenafil (50mg)Cadila Pharmaceuticals Limited.
Silagra 50mg TabletSildenafil (50mg)S.R. Drug Laboratories Pvt. Ltd.
Vega 50mg TabletSildenafil (50mg)Mankind Pharma Ltd
Xcite 25mg TabletSildenafil (25mg)Alive Pharmaceutical. Pvt. Ltd.
Zenegra 100 100mg TabletSildenafil (100mg)Alkem Laboratories Ltd.
Zenegra 50 50mg TabletSildenafil (50mg)Alkem Laboratories Ltd.
Adams Delight 100mg TabletSildenafil (100mg)Ind Swift Laboratories Ltdstrip of 4 tablets
Aerogra 50mg TabletSildenafil (50mg)Ritz Pharmastrip of 4 tablets
Agra 100mg TabletSildenafil (100mg)Alliaance Biotechstrip of 4 tablets
Agra 50mg TabletSildenafil (50mg)Alliaance Biotechstrip of 4 tablets
Air Bus 50mg TabletSildenafil (50mg)Sanify Healthcare Pvt Ltdstrip of 4 tablets
Airbus 50mg TabletSildenafil (50mg)Syntonic Lifesciencesstrip of 4 tablets
Alivher TabletSildenafil (25mg)Akumentis Healthcare Ltdstrip of 10 tablets
Alpink 100mg TabletSildenafil (100mg)H.L Healthcare Pvt Ltdstrip of 10 tablets
Alsigra 100mg TabletSildenafil (100mg)Alembic Pharmaceuticals Ltdstrip of 4 tablets
Alsigra 25mg TabletSildenafil (25mg)Alembic Pharmaceuticals Ltdstrip of 4 tablets
Alsigra 50mg TabletSildenafil (50mg)Alembic Pharmaceuticals Ltdstrip of 10 tablets
Androz 25mg TabletSildenafil (25mg)Torrent Pharmaceuticals Ltdstrip of 10 tablets
Androz 50mg TabletSildenafil (50mg)Torrent Pharmaceuticals Ltdstrip of 10 tablets
Aquaforce 100mg TabletSildenafil (100mg)Aquadry Pharma Pvt Ltdstrip of 4 tablets

Showing 30 of 392 catalog products. Search the full catalog in the app.

Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Storage for Sildenafil Tablets, USP: Store at controlled room temperature 20º to 25ºC (68º to 77ºF);

Storage information from the U.S. FDA-approved label.

Medicines for the same conditions

Sildenafil is recorded in the NepalDoc medicine catalog for: Erectile dysfunction, Pulmonary arterial hypertension.

For Erectile dysfunction: Tadalafil.

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+ Safety information

This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. A catalog listing does not guarantee that a medicine is in stock at any pharmacy.

NepalDoc — Nepal's Healthcare Super-App (Beta) / नेपालको स्वास्थ्य सुपर-एप (बेटा).
Medicine information only — not medical advice. Confirm with a pharmacist or doctor.