Spironolactone is an aldosterone antagonist indicated for: The treatment of NYHA Class III-IV heart failure and reduced ejection fraction to increase survival, manage edema, and to reduce the need for hospitalization for heart failure., Use as an add-on therapy for the treatment of hypertension, to lower blood pressure.
From the U.S. FDA-approved label for Spironolactone. Full label: DailyMed.
Spironolactone is an aldosterone antagonist indicated for: The treatment of NYHA Class III-IV heart failure and reduced ejection fraction to increase survival, manage edema, and to reduce the need for hospitalization for heart failure., Use as an add-on therapy for the treatment of hypertension, to lower blood pressure.
From the U.S. FDA-approved label for Spironolactone. Full label: DailyMed.
Heart Failure: Initiate treatment at 25 mg once daily., Hypertension: Initiate treatment at 25 mg to 100 mg daily in either single or divided doses., Edema: Initiate therapy in a hospital setting and titrate slowly. The recommended initial daily dose is 100 mg in single or divided doses., Primary hyperaldosteronism: Initiate treatment at 100 mg to 400 mg in preparation for surgery. In patients unsuitable for surgery use the lowest effective dosage determined for the individual patient.
Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.
Spironolactone tablets are contraindicated in the patients with: Hyperkalemia, Addison's disease, Concomitant use of eplerenone Spironolactone tablets are contraindicated in patients with: Hyperkalemia, Addison's disease, Concomitant use of eplerenone
Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.
Hyperkalemia: Monitor serum potassium within one week of initiation and regularly thereafter., Hypotension and Worsening Renal Function: Monitor volume status and renal function periodically., Electrolyte and Metabolic Abnormalities: Monitor serum electrolytes, uric acid and blood glucose periodically., Gynecomastia: Spironolactone can cause gynecomastia. 5.1 Hyperkalemia Spironolactone can cause hyperkalemia.
Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.
The following clinically significant adverse reactions are described elsewhere in the labeling: Hyperkalemia, Hypotension and Worsening Renal Function, Electrolyte and Metabolic Abnormalities, Gynecomastia, Impaired neurological function/ coma in patients with hepatic impairment, cirrhosis and ascites The following adverse reactions associated with the use of spironolactone were identified in clinical trials or postmarketing…
Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.
35 products from 17 makers in the NepalDoc medicine catalog use this generic:
| Brand | Composition | Maker | Pack |
|---|---|---|---|
| Aldace 100 100mg Tablet | Spironolactone (100mg) | Omnica Laboratories Pvt. Ltd.. | |
| Aldace 25 25mg Tablet | Spironolactone (25mg) | Omnica Laboratories Pvt. Ltd.. | |
| Aldactone 100 100mg Tablet | Spironolactone (100mg) | RPG Life Sciences Ltd. | |
| Aldactone 25 25mg Tablet | Spironolactone (25mg) | RPG Life Sciences Ltd. | |
| Ema 25mg Tablet | Spironolactone (25mg) | Quest Pharmaceuticals Pvt. Ltd. | |
| Ema 50mg Tablet | Spironolactone (50mg) | Quest Pharmaceuticals Pvt. Ltd. | |
| Rosetone 100mg Tablet | Spironolactone (100mg) | CTL Pharmaceuticals Pvt. Ltd. | |
| Rosetone 12.5mg Tablet | Spironolactone (12.5mg) | CTL Pharmaceuticals Pvt. Ltd. | |
| Rosetone 25mg Tablet | Spironolactone (25mg) | CTL Pharmaceuticals Pvt. Ltd. | |
| Rosetone 50mg Tablet | Spironolactone (50mg) | CTL Pharmaceuticals Pvt. Ltd. | |
| Spilac 25mg Tablet | Spironolactone (25mg) | Biogain Remedies Pvt. Ltd. | |
| Spilac 50mg Tablet | Spironolactone (50mg) | Biogain Remedies Pvt. Ltd. | |
| Spirolac 12.5 12.5mg Tablet | Spironolactone (12.5mg) | National Healthcare Pvt. Ltd. | |
| Spirolac 25 25mg Tablet | Spironolactone (25mg) | National Healthcare Pvt. Ltd. | |
| Spril 100 100mg Tablet | Spironolactone (100mg) | Lomus Pharmaceutical Pvt. Ltd. | |
| Spril 25 25mg Tablet | Spironolactone (25mg) | Lomus Pharmaceutical Pvt. Ltd. | |
| Aldace 25mg Tablet | Spironolactone (25mg) | Omnica Laboratories | strip of 10 tablets |
| Aldactone 100 Tablet | Spironolactone (100mg) | RPG Life Sciences Ltd | strip of 15 tablets |
| Aldactone 50 Tablet | Spironolactone (50mg) | RPG Life Sciences Ltd | strip of 15 tablets |
| Aldactone Tablet | Spironolactone (25mg) | RPG Life Sciences Ltd | strip of 15 tablets |
| Aldotone 50mg Tablet | Spironolactone (50mg) | Samarth Life Sciences Pvt Ltd | strip of 15 tablets |
| Cglactone 100mg Tablet | Spironolactone (100mg) | Cmg Biotech Pvt Ltd | strip of 10 tablets |
| Cglactone 25mg Tablet | Spironolactone (25mg) | Cmg Biotech Pvt Ltd | strip of 10 tablets |
| Cglactone 50mg Tablet | Spironolactone (50mg) | Cmg Biotech Pvt Ltd | strip of 10 tablets |
| Edeflow 100 Tablet | Spironolactone (100mg) | Leeford Healthcare Ltd | strip of 10 tablets |
| Edeflow 50 Tablet | Spironolactone (50mg) | Leeford Healthcare Ltd | strip of 10 tablets |
| Genericart Spironolactone 25mg Tablet | Spironolactone (25mg) | Swast Aushadhi Seva Generic Medicine Store | strip of 10 tablets |
| Lactone 100mg Tablet | Spironolactone (100mg) | Aimil Pharmaceuticals India Ltd | strip of 6 tablets |
| Silectone 100 Tablet | Spironolactone (100mg) | Johnlee Pharmaceuticals Pvt Ltd | strip of 10 tablets |
| Silectone 25 Tablet | Spironolactone (25mg) | Johnlee Pharmaceuticals Pvt Ltd | strip of 10 tablets |
Showing 30 of 35 catalog products. Search the full catalog in the app.
Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.
Keep this and all drugs out of the reach of children. Storage Store at 20° to 25°C (68° to 77°F). Protect from light.
Storage information from the U.S. FDA-approved label.
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.