Tacrolimus capsules are a calcineurin-inhibitor immunosuppressant indicated for the prophylaxis of organ rejection in adult patients receiving allogeneic liver, kidney, or heart transplants, and pediatric patients receiving allogenic liver transplants in combination with other immunosuppressants.
From the U.S. FDA-approved label for Tacrolimus. Full label: DailyMed.
Tacrolimus capsules are a calcineurin-inhibitor immunosuppressant indicated for the prophylaxis of organ rejection in adult patients receiving allogeneic liver, kidney, or heart transplants, and pediatric patients receiving allogenic liver transplants in combination with other immunosuppressants. Additional pediatric use information is approved for Astellas Pharma US, Inc.’s Prograf (tacrolimus) products. However, due to Astellas Pharma US, Inc.’s marketing exclusivity rights, this drug product is not labeled with that information.
From the U.S. FDA-approved label for Tacrolimus. Full label: DailyMed.
Administer capsules consistently with or without food., Therapeutic drug monitoring is recommended., Avoid eating grapefruit or drinking grapefruit juice., See dosage adjustments for African-American patients, hepatic and renal impaired., For complete dosing information, see Full Prescribing Information. Tacrolimus capsules are not interchangeable or substitutable for other tacrolimus extended-release products. This is because rate of absorption following the administration of an extended-release tacrolimus product is not equivalent to that of an immediate-release tacrolimus drug product.
Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.
Tacrolimus capsules are contraindicated in patients with a hypersensitivity to tacrolimus. Hypersensitivity symptoms reported include dyspnea, rash, pruritus, and acute respiratory distress syndrome., Hypersensitivity to tacrolimus or HCO-60 (polyoxyl 60 hydrogenated castor oil).
Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.
Not Interchangeable with Extended-Release Tacrolimus Products – Medication Errors: Instruct patients or caregivers to recognize the appearance of tacrolimus capsules., New Onset Diabetes After Transplant: Monitor blood glucose., Nephrotoxicity (acute and/or chronic): Reduce the dose; use caution with other nephrotoxic drugs., Neurotoxicity: Including risk of Posterior Reversible Encephalopathy Syndrome (PRES); monitor for neurologic abnormalities; reduce or discontinue tacrolimus., Hyperkalemia: Monitor serum potassium levels.
Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.
The following serious and otherwise important adverse drug reactions are discussed in greater detail in other sections of labeling: Lymphoma and Other Malignancies, Serious Infections, New Onset Diabetes After Transplant, Nephrotoxicity, Neurotoxicity, Hyperkalemia, Hypertension, Anaphylactic Reactions with Tacrolimus Injection, Myocardial Hypertrophy, Pure Red Cell Aplasia, Thrombotic Microangiopathy, Including Hemolytic…
Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.
340 products from 163 makers in the NepalDoc medicine catalog use this generic:
| Brand | Composition | Maker | Pack |
|---|---|---|---|
| Pangraf 0.5mg Capsule | Tacrolimus (0.5mg) | Panacea Biotec Ltd. | |
| Pangraf 1mg Capsule | Tacrolimus (1mg) | Panacea Biotec Ltd. | |
| Pangraf 2mg Tablet | Tacrolimus (2mg) | Panacea Biotec Ltd. | |
| Seegraf 0.5 0.5mg Capsule | Tacrolimus (0.5mg) | Micro Labs Ltd. | |
| Seegraf 1 1mg Capsule | Tacrolimus (1mg) | Micro Labs Ltd. | |
| Takfa 0.5mg Capsule | Tacrolimus (0.5mg) | Intas Pharmaceuticals Ltd. | |
| Takfa 1mg Capsule | Tacrolimus (1mg) | Intas Pharmaceuticals Ltd. | |
| Takfa 2mg Capsule | Tacrolimus (2mg) | Intas Pharmaceuticals Ltd. | |
| Takfa Capsule | Tacrolimus | Cipla Ltd. | |
| Abitac 1% Ointment | Tacrolimus (1% w/w) | Abigail Care Pharmaceutical | tube of 10 gm Ointment |
| Acomuskin 0.5 Capsule | Tacrolimus (0.5mg) | Accord Pharmaceuticals | strip of 10 capsules |
| Acomuskin 1 Capsule | Tacrolimus (1mg) | Accord Pharmaceuticals | strip of 10 capsules |
| Acroli Forte Ointment | Tacrolimus (0.1% w/w) | Psycormedies | tube of 10 gm Ointment |
| Acroli Ointment | Tacrolimus (0.03% w/w) | Psycormedies | tube of 10 gm Ointment |
| Acromus 0.1% Eye Ointment | Tacrolimus (0.1%) | Pharmatak Opthalmics Pvt Ltd | tube of 5 gm Eye Ointment |
| Advagraf 0.5mg Capsule PR | Tacrolimus (0.5mg) | Astellas Pharma Inc | strip of 10 capsule pr |
| Advagraf 1mg Capsule PR | Tacrolimus (1mg) | Astellas Pharma Inc | strip of 10 capsule pr |
| Advagraf 5mg Capsule PR | Tacrolimus (5mg) | Astellas Pharma Inc | strip of 10 capsule pr |
| Alagraf 0.5 Capsule | Tacrolimus (0.5mg) | Alacris Healthcare Pvt Ltd | strip of 10 capsules |
| Amigraf 0.5 Capsule | Tacrolimus (0.5mg) | Biokindle Lifesciences Pvt Ltd | strip of 10 capsules |
| Astacro Ointment | Tacrolimus (0.03% w/w) | Astley Life Sciences Pvt Ltd | tube of 10 gm Ointment |
| Astacro Plus Ointment | Tacrolimus (0.1% w/w) | Astley Life Sciences Pvt Ltd | tube of 10 gm Ointment |
| Atograf Forte 0.1% Ointment | Tacrolimus (0.1% w/w) | Amwill Healthcare | tube of 20 gm Ointment |
| Atomus Ointment | Tacrolimus (0.1% w/w) | Grefith Life Sciences Pvt Ltd | tube of 10 gm Ointment |
| Biomus 0.25mg Tablet | Tacrolimus (0.25mg) | Alniche Life Sciences Pvt Ltd | strip of 10 tablets |
| Biomus 1 Capsule | Tacrolimus (1mg) | Alniche Life Sciences Pvt Ltd | strip of 10 capsules |
| Biomus 2mg Capsule | Tacrolimus (2mg) | Alniche Life Sciences Pvt Ltd | strip of 10 capsules |
| Biomus-Forte Ointment | Tacrolimus (0.1% w/w) | Alniche Life Sciences Pvt Ltd | tube of 10 gm Ointment |
| Citac 1mg Capsule | Tacrolimus (1mg) | Advaith Life Sciences Pvt Ltd | strip of 10 capsules |
| Citac 2mg Capsule | Tacrolimus (2mg) | Advaith Life Sciences Pvt Ltd | strip of 10 capsules |
Showing 30 of 340 catalog products. Search the full catalog in the app.
Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.
Store and Dispense Tacrolimus capsules, USP should be stored at 20° to 25°C (68° to 77°F).
Storage information from the U.S. FDA-approved label.
Tacrolimus is recorded in the NepalDoc medicine catalog for: Prophylaxis of rejection in kidney, liver & cardiac graft transplant, Atopic dermatitis, Allergic contact dermatitis, Severe eczema, Psoriasis.
For Atopic dermatitis: Hydrocortisone.
For Psoriasis: Salicylic acid.
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. A catalog listing does not guarantee that a medicine is in stock at any pharmacy.
