Dorzolamide hydrochloride and timolol maleate ophthalmic solution is indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers (failed to achieve target IOP determined after multiple measurements over time).
From the U.S. FDA-approved label for Timolol. Full label: DailyMed.
Dorzolamide hydrochloride and timolol maleate ophthalmic solution is indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers (failed to achieve target IOP determined after multiple measurements over time). The IOP-lowering of dorzolamide hydrochloride and timolol maleate ophthalmic solution administered twice a day was slightly less than that seen with the concomitant administration of 0.5% timolol administered twice a day and 2% dorzolamide administered three times a day.
From the U.S. FDA-approved label for Timolol. Full label: DailyMed.
2 DOSAGE & ADMINISTRATION The dose is one drop of dorzolamide hydrochloride and timolol maleate ophthalmic solution in the affected eye(s) two times daily. If more than one topical ophthalmic drug is being used, the drugs should be administered at least five minutes apart. The dose is one drop of dorzolamide hydrochloride and timolol maleate ophthalmic solution in the affected eye(s) two times daily.
Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.
Dorzolamide hydrochloride and timolol maleate ophthalmic solution is contraindicated in patients with: Bronchial asthma or a history of bronchial asthma, severe chronic obstructive pulmonary disease. Sinus bradycardia, second or third degree atrioventricular block, overt cardiac failure, cardiogenic shock. Hypersensitivity to any component of this product.
Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.
Potentiation of Respiratory Reactions Including Asthma Cardiac Failure Sulfonamide Hypersensitivity Obstructive Pulmonary Disease Increased Reactivity to Allergens Potentiation of Muscle Weakness Masking of Hypoglycemic Symptoms in Patients with Diabetes Mellitus Masking of Thyrotoxicosis Renal and Hepatic Impairment Impairment of Beta-Adrenergically Mediated Reflexes During Surgery 5.1 Potentiation of Respiratory Reactions Including Asthma Dorzolamide hydrochloride and timolol maleate ophthalmic solution contains timolol maleate, a beta-adrenergic blocking agent; and although administered topically, is absorbed systemically.
Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.
The most frequently reported adverse reactions were taste perversion (bitter, sour, or unusual taste) or ocular burning and/or stinging in up to 30% of patients. Conjunctival hyperemia, blurred vision, superficial punctate keratitis or eye itching were reported between 5 to 15% of patients. To report SUSPECTED ADVERSE REACTIONS, contact at 1-833-856-0880 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.
81 products from 67 makers in the NepalDoc medicine catalog use this generic:
| Brand | Composition | Maker | Pack |
|---|---|---|---|
| Appatim Eye Drop | Timolol (0.5%) | Appasamy Ocular Device Pvt Ltd | packet of 5 ml Eye Drop |
| Aurotim Eye Drop | Timolol (0.5% w/w) | Aurolab | bottle of 5 ml Eye Drop |
| C Pin Eye Drop | Timolol (0.25% w/v) | Calibre Pharmaceutical | packet of 3 ml Eye Drop |
| Domolol 0.25% Eye Drop | Timolol (0.25% w/v) | Doeshealth Systems Private Limited | bottle of 5 ml Eye Drop |
| Glauc Aid Eye Drop | Timolol (NA) | Nri Vision Care India Limited | packet of 5 ml Eye Drop |
| Glucomol 0.25% Eye Drop | Timolol (0.25% w/w) | Allergan India Pvt Ltd | bottle of 5 ml Eye Drop |
| Glucomol 0.5% Eye Drop | Timolol (0.5% w/v) | Allergan India Pvt Ltd | bottle of 5 ml Eye Drop |
| Glucotim 0.25% Eye Drop | Timolol (0.25%) | Centaur Pharmaceuticals Pvt Ltd | packet of 5 ml Eye Drop |
| Glucotim 0.5% Eye Drop | Timolol (0.5%) | Centaur Pharmaceuticals Pvt Ltd | packet of 5 ml Eye Drop |
| Glucotim LA Eye Drop | Timolol (0.5% w/v) | Centaur Pharmaceuticals Pvt Ltd | packet of 5 ml Ophthalmic Solution |
| Gludrop Eye Drop | Timolol (0.5% w/v) | Optho Life Sciences Pvt Ltd | bottle of 5 ml Eye Drop |
| Glunil Eye Drop | Timolol (0.5% w/v) | Pharmtak Ophtalmics India Pvt Ltd | packet of 5 ml Eye Drop |
| Gromol 0.5% Eye Drop | Timolol (0.5% w/v) | Growell Vision | bottle of 5 ml Eye Drop |
| Iotim Eye Drop | Timolol (0.5% w/v) | FDC Ltd | bottle of 5 ml Eye Drop |
| Lopres 0.25% Eye Drop | Timolol (0.25% w/v) | Micro Labs Ltd | bottle of 5 ml Eye Drop |
| Lopres 0.5% Eye Drop | Timolol (0.5% w/v) | Micro Labs Ltd | packet of 5 ml Eye Drop |
| Mop Eye Drop | Timolol (0.5% w/v) | Medivision Pharm | packet of 5 ml Eye Drop |
| Nayatim 0.5% Eye Drop | Timolol (0.5% w/v) | BMW Pharmaco India Pvt. Ltd. | bottle of 5 ml Eye Drop |
| Nyolol Eye Drop | Timolol (0.5% w/v) | Novartis India Ltd | packet of 5 ml Eye Drop |
| Ocobar 0.25% Eye Drop | Timolol (0.25% w/v) | PCI Pharmaceuticals | bottle of 5 ml Eye Drop |
| Ocobar 0.5% Eye Drop | Timolol (0.5% w/v) | PCI Pharmaceuticals | bottle of 5 ml Eye Drop |
| Ocupress 0.5% Eye Drop | Timolol (0.5%) | Cadila Pharmaceuticals Ltd | packet of 5 ml Eye Drop |
| Ocutim 0.25% Eye Drop | Timolol (0.25% w/v) | Cipla Ltd | packet of 5 ml Eye Drop |
| Ocutim 0.5% Eye Drop | Timolol (0.5% w/v) | Cipla Ltd | packet of 5 ml Eye Drop |
| Sensolol 0.5% Eye Drop | Timolol (0.5% w/v) | Senses Pharmaceuticals Ltd | packet of 5 ml Eye Drop |
| StayHappi Timolol 0.5% Eye Drop | Timolol (0.5% w/v) | Sarvagunaushdhi Pvt Ltd | bottle of 5 ml Eye Drop |
| Stimo 0.5% Eye Drop | Timolol (0.5% w/v) | Zeotec Life Science Pvt Ltd | bottle of 5 ml Eye Drop |
| T Lol 0.5% Eye Drop | Timolol (0.5% w/v) | Agaaz Ophthalmics | bottle of 10 ml Eye Drop |
| Tee 50 Eye Drop | Timolol (0.5% w/v) | Mmatrics Pharmaceuticals | packet of 5 ml Eye Drop |
| Teemol 0.5% Eye Drop | Timolol (0.5% w/v) | Indiana Opthalmics | bottle of 10 ml Eye Drop |
Showing 30 of 81 catalog products. Search the full catalog in the app.
Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.
Storage: Store dorzolamide hydrochloride and timolol maleate ophthalmic solution at 20° to 25°C (68° to 77°F). Protect from light.
Storage information from the U.S. FDA-approved label.
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.
