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Vincristine

Immunomodulators, Antineoplastic and Medicines used in Palliative Care
Powder · Injection1 mg15 brands · 12 makers
Vincristine is listed in Nepal's National List of Essential Medicines (NLEM, Sixth Revision 2021) under Immunomodulators, Antineoplastic and Medicines used in Palliative Care. According to its FDA label, it is Sulfate Injection is indicated in acute leukemia. 15 brand names for this medicine are listed in the NepalDoc medicine catalog.
Generic namevincristine
Therapeutic classImmunomodulators, Antineoplastic and Medicines used in Palliative Care > 8.2.1 Cytotoxic medicines (complementary list)
Form & strength (NLEM)Powder for injection:1 mg (sulfate) in vial
Source / स्रोतNational List of Essential Medicines Nepal (2021); NepalDoc medicine catalog

What it's for

Vincristine Sulfate Injection is indicated in acute leukemia. Vincristine Sulfate Injection has also been shown to be useful in combination with other oncolytic agents in Hodgkin's disease, non–Hodgkin's malignant lymphomas, rhabdomyosarcoma, neuroblastoma, and Wilms' tumor.

From the U.S. FDA-approved label for Vincristine. Full label: DailyMed.

Vincristine Sulfate Injection is indicated in acute leukemia. Vincristine Sulfate Injection has also been shown to be useful in combination with other oncolytic agents in Hodgkin's disease, non–Hodgkin's malignant lymphomas, rhabdomyosarcoma, neuroblastoma, and Wilms' tumor.

From the U.S. FDA-approved label for Vincristine. Full label: DailyMed.

This preparation is for intravenous use only (see WARNINGS ). Neurotoxicity appears to be dose related. Extreme care must be used in calculating and administering the dose of Vincristine Sulfate Injection since overdosage may have a very serious or fatal outcome.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Patients with the demyelinating form of Charcot–Marie–Tooth syndrome should not be given Vincristine Sulfate Injection. Careful attention should be given to those conditions listed under WARNINGS and PRECAUTIONS.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

This preparation is for intravenous use only. It should be administered by individuals experienced in the administration of Vincristine Sulfate Injection. The intrathecal administration of Vincristine Sulfate Injection usually results in death. To reduce the potential for fatal medication errors due to incorrect route of administration, Vincristine Sulfate Injection should be diluted in a flexible plastic container and prominently labeled as indicated "FOR INTRAVENOUS USE ONLY – FATAL IF GIVEN BY OTHER ROUTES." See OVERDOSAGE section for the treatment of patients given intrathecal Vincristine Sulfate Injection.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

Prior to the use of this drug, patients and/or their parents/guardian should be advised of the possibility of untoward symptoms. In general, adverse reactions are reversible and are related to dosage. The most common adverse reaction is hair loss; the most troublesome adverse reactions are neuromuscular in origin.

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

15 products from 12 makers in the NepalDoc medicine catalog use this generic:

BrandCompositionMakerPack
Alcrist 1mg InjectionVincristine (1mg)Alkem Laboratories Ltdvial of 1 Injection
B Cristine 1mg InjectionVincristine (1mg)Health Biotech Limitedvial of 1 Injection
Biocristin 1mg InjectionVincristine (1mg)Biochem Pharmaceutical Industriesvial of 1 Injection
Biocristin AQ 1mg InjectionVincristine (1mg)Biochem Pharmaceutical Industriesvial of 1 ml Injection
Cytocristin 1mg InjectionVincristine (1mg)Cipla Ltdvial of 1 ml Injection
Cytocristin 2mg InjectionVincristine (2mg)Cipla Ltdvial of 2 ml Injection
Ivin 1mg InjectionVincristine (1mg)Vhb Life Sciences Incvial of 1 ml Injection
Oncocristin AQ 1mg InjectionVincristine (1mg)Sun Pharmaceutical Industries Ltdvial of 1 ml Injection
Onvinc 1mg InjectionVincristine (1mg)Neon Laboratories Ltdvial of 1 Injection
Vcad 1mg InjectionVincristine (1mg)Cadila Pharmaceuticals Ltdvial of 1 Injection
Vincreta 1mg InjectionVincristine (1mg)Metta Life Sciences Private Limitedvial of 1 Injection
Vincryst 1mg InjectionVincristine (1mg)Chandra Bhagat Pharma Pvt Ltdvial of 1 ml Injection
Vinlon 1mg InjectionVincristine (1mg)Celon Laboratories Ltdvial of 1 ml Injection
Vinrosa 1mg InjectionVincristine (1mg)Naprod Life Sciencesvial of 1 ml Injection
Vinstin 1mg InjectionVincristine (1mg)Vhb Life Sciences Incvial of 1 Injection

Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

This product should be refrigerated between 2°C–8°C (36°F–46°F). Discard unused solution. Protect from light. Store Upright.

Storage information from the U.S. FDA-approved label.

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+ Safety information

This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.

NepalDoc — Nepal's Healthcare Super-App (Beta) / नेपालको स्वास्थ्य सुपर-एप (बेटा).
Medicine information only — not medical advice. Confirm with a pharmacist or doctor.