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Warfarin

Vitamin K antagonist
Tablet1mg · 2 mg · 5 mg17 brands · 7 makers
Warfarin is a vitamin K antagonist used for prophylaxis and treatment of venous thrombosis and its extension, pulmonary embolism (PE). Warfarin is listed in Nepal's National List of Essential Medicines (NLEM, Sixth Revision 2021) under Medicines Affecting the Blood.
Generic namewarfarin
Therapeutic classMedicines Affecting the Blood > 10.2 Medicines affecting coagulation
Form & strength (NLEM)Tablet: 1mg, 2 mg, 5 mg (sodium salt)
Source / स्रोतNational List of Essential Medicines Nepal (2021); NepalDoc medicine catalog

What it's for

Warfarin sodium tablets are indicated for: Prophylaxis and treatment of venous thrombosis and its extension, pulmonary embolism (PE). Prophylaxis and treatment of thromboembolic complications associated with atrial fibrillation (AF) and/or cardiac valve replacement.

From the U.S. FDA-approved label for Warfarin. Full label: DailyMed.

Warfarin sodium tablets are indicated for: Prophylaxis and treatment of venous thrombosis and its extension, pulmonary embolism (PE). Prophylaxis and treatment of thromboembolic complications associated with atrial fibrillation (AF) and/or cardiac valve replacement. Reduction in the risk of death, recurrent myocardial infarction (MI), and thromboembolic events such as stroke or systemic embolization after myocardial infarction.

From the U.S. FDA-approved label for Warfarin. Full label: DailyMed.

Individualize dosing regimen for each patient, and adjust based on INR response. Knowledge of genotype can inform initial dose selection. Monitoring: Obtain daily INR determinations upon initiation until stable in the therapeutic range.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Warfarin sodium is contraindicated in: Pregnancy Warfarin sodium is contraindicated in women who are pregnant except in pregnant women with mechanical heart valves, who are at high risk of thromboembolism. Warfarin sodium can cause fetal harm when administered to a pregnant woman. Warfarin sodium exposure during pregnancy causes a recognized pattern of major congenital malformations (warfarin embryopathy and fetotoxicity), fatal fetal hemorrhage, and an increased risk of spontaneous abortion and fetal mortality.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Tissue necrosis: Necrosis or gangrene of skin or other tissues can occur, with severe cases requiring debridement or amputation. Discontinue warfarin sodium and consider alternative anticoagulants if necessary. Calciphylaxis: Fatal and serious cases have occurred. Discontinue warfarin sodium and consider alternative anticoagulation therapy. Acute kidney injury may occur during episodes of excessive anticoagulation and hematuria. Systemic atheroemboli and cholesterol microemboli: Some cases have progressed to necrosis or death. Discontinue warfarin sodium if such emboli occur.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

The following serious adverse reactions to warfarin sodium are discussed in greater detail in other sections of the labeling: Hemorrhage Tissue Necrosis Calciphylaxis Acute Kidney Injury Systemic Atheroemboli and Cholesterol Microemboli Limb Ischemia, Necrosis, and Gangrene in Patients with HIT and HITTS Other Clinical Settings with Increased Risks Other adverse reactions to warfarin sodium include: Immune system disorders:…

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

17 products from 7 makers in the NepalDoc medicine catalog use this generic:

BrandCompositionMakerPack
Cofarin 1mg TabletWarfarin (1mg)East West Pharmastrip of 10 tablets
Cofarin 2mg TabletWarfarin (2mg)East West Pharmastrip of 10 tablets
Cofarin 3mg TabletWarfarin (3mg)East West Pharmastrip of 10 tablets
Cofarin 5mg TabletWarfarin (5mg)East West Pharmastrip of 10 tablets
Genericart Warfarin 2mg TabletWarfarin (2mg)Swast Aushadhi Seva Generic Medicine Storestrip of 10 tablets
Mywarf TabletWarfarin (5mg)Parnasa Mediworld Pvt Ltdstrip of 15 tablets
Sofarin 5mg TabletWarfarin (5mg)Samarth Life Sciences Pvt Ltdstrip of 10 tablets
Uniwarfin 1mg TabletWarfarin (1mg)Torrent Pharmaceuticals Ltdstrip of 10 tablets
Uniwarfin 2mg TabletWarfarin (2mg)Torrent Pharmaceuticals Ltdstrip of 10 tablets
Uniwarfin 5mg TabletWarfarin (5mg)Torrent Pharmaceuticals Ltdstrip of 10 tablets
WAF 5 TabletWarfarin (5mg)Johnlee Pharmaceuticals Pvt Ltdstrip of 10 tablets
Warf 1 TabletWarfarin (1mg)Cipla Ltdstrip of 30 tablets
Warf 10mg TabletWarfarin (10mg)Cipla Ltdstrip of 10 tablets
Warf 2 TabletWarfarin (2mg)Cipla Ltdstrip of 30 tablets
Warf 3 TabletWarfarin (3mg)Cipla Ltdstrip of 30 tablets
Warf 4mg TabletWarfarin (4mg)Cipla Ltdstrip of 10 tablets
Warf 5 TabletWarfarin (5mg)Cipla Ltdstrip of 30 tablets

Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Protect from light. Keep tightly closed. Store at 20° to 25°C (68° to 77°F).

Storage information from the U.S. FDA-approved label.

Medicines for the same conditions

Warfarin is recorded in the NepalDoc medicine catalog for: Venous thromboembolism, Stroke prevention, Deep vein thrombosis.

For Venous thromboembolism: Enoxaparin.

For Stroke prevention: Nifedipine, Nimodipine, Rosuvastatin.

For Deep vein thrombosis: Enoxaparin.

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+ Safety information

This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.

NepalDoc — Nepal's Healthcare Super-App (Beta) / नेपालको स्वास्थ्य सुपर-एप (बेटा).
Medicine information only — not medical advice. Confirm with a pharmacist or doctor.