Zoledronic acid

Infusion given intravenously over no less than 15 minutes: Treatment of postmenopausal osteoporosis; treatment to increase bone mass in men with osteoporosis: treatment and prevention of glucocorticoid-induced osteoporosis: 5 mg once a year Prevention of postmenopausal osteoporosis: 5 mg once every 2 years Treatment of Paget’s disease of bone: a single 5 mg infusion.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Zoledronic acid injection is contraindicated in patients with the following conditions: Hypocalcemia, Creatinine clearance less than 35 mL/min and in those with evidence of acute renal impairment due to an increased risk of renal failure., Known hypersensitivity to zoledronic acid or any components of zoledronic acid injection. Hypersensitivity reactions including urticaria, angioedema, and anaphylactic reaction/shock have been reported.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Products Containing Same Active Ingredient: Patients receiving Zometa should not receive zoledronic acid injection Hypocalcemia may worsen during treatment. Patients must be adequately supplemented with calcium and vitamin D Renal Impairment: A single dose should not exceed 5 mg and the duration of infusion should be no less than 15 minutes. Renal toxicity may be greater in patients with underlying renal impairment or with other risk factors, including advanced age or dehydration. Monitor creatinine clearance before each dose Osteonecrosis of the Jaw (ONJ) has been reported.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

The most common adverse reactions (greater than 10%) were pyrexia, myalgia, headache, arthralgia, pain in extremity. Other important adverse reactions were flu-like illness, nausea, vomiting, diarrhea, and eye inflammation. To report SUSPECTED ADVERSE REACTIONS, contact Fresenius Kabi USA, LLC at 1-800-551-7176 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

47 products from 39 makers in the NepalDoc medicine catalog use this generic:

Showing 30 of 47 catalog products. Search the full catalog in the app.

Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Storage Store at 25°C (77°F);

Storage information from the U.S. FDA-approved label.