Dobutamine Hydrochloride in 5% Dextrose Injection is indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures. Experience with intravenous dobutamine in controlled trials does not extend beyond 48 hours of repeated boluses and/or continuous infusions.
From the U.S. FDA-approved label for Dobutamine. Full label: DailyMed.
Dobutamine Hydrochloride in 5% Dextrose Injection is indicated when parenteral therapy is necessary for inotropic support in the short-term treatment of patients with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures. Experience with intravenous dobutamine in controlled trials does not extend beyond 48 hours of repeated boluses and/or continuous infusions. Whether given orally, continuously intravenously, or intermittently intravenously, neither dobutamine nor any other cyclic-AMP-dependent inotrope has been shown in controlled trials to be safe or effective in the long-term treatment of congestive heart failure. In controlled trials of chronic oral therapy with various such agents, symptoms were not consistently alleviated, and the cyclic-AMP-dependent inotropes were consistently associated with increased risks of hospitalization and death. Patients with NYHA Class IV symptoms appeared to be at particular risk.
From the U.S. FDA-approved label for Dobutamine. Full label: DailyMed.
Recommended Dosage Dobutamine Hydrochloride in 5% Dextrose Injection is administered intravenously through a suitable intravenous catheter or needle. A calibrated electronic infusion device is recommended for controlling the rate of flow in mL/hour or drops/minute.
Directions from the U.S. FDA-approved label for Dobutamine — your doctor or pharmacist may advise differently.
Dobutamine Hydrochloride in 5% Dextrose Injection is contraindicated in patients with idiopathic hypertrophic subaortic stenosis and in patients who have shown previous manifestations of hypersensitivity to dobutamine. Solutions containing dextrose may be contraindicated in patients with known allergy to corn or corn products.
Excerpt from the U.S. FDA-approved label for Dobutamine. Talk to a pharmacist or doctor before use.
Increase in Heart Rate or Blood Pressure Dobutamine Hydrochloride in 5% Dextrose Injection may cause a marked increase in heart rate or blood pressure, especially systolic pressure. Approximately 10% of adult patients in clinical studies have had rate increases of 30 beats/minute or more, and about 7.5% have had a 50-mm Hg or greater increase in systolic pressure. Usually, reduction of dosage reverses these effects. Because dobutamine facilitates atrioventricular conduction, patients with atrial fibrillation are at risk of developing rapid ventricular response.
Warnings and precautions excerpt from the U.S. FDA-approved label for Dobutamine — not a complete list. Talk to a pharmacist or doctor before use.
Increased Heart Rate, Blood Pressure, and Ventricular Ectopic Activity A 10 to 20-mm Hg increase in systolic blood pressure and an increase in heart rate of 5 to 15 beats/minute have been noted in most patients (see WARNINGS regarding exaggerated chronotropic and pressor effects). Approximately 5% of adult patients have had increased premature ventricular beats during infusions. These effects are dose related.
Excerpt from the U.S. FDA-approved label for Dobutamine — not a complete list. Talk to a pharmacist or doctor about side effects.
4 brands · 4 makers in the NepalDoc catalog — see the full Dobutamine guide →
Protect from freezing. Stored at room temperature (25°C);
Storage information from the U.S. FDA-approved label for Dobutamine.
What is Cardiject?
Cardiject 250mg Injection is a Dobutamine medicine made by Sun Pharmaceutical Industries Ltd. It comes as 250mg Injection.
What is the generic name of Cardiject?
The generic name of Cardiject is Dobutamine.
Which brands of Dobutamine are available in Nepal?
4 brands of Dobutamine are listed in the NepalDoc catalog, from 4 makers — including Dobucin 250mg Injection, Dobufast 250mg Injection, Dobutrex 250mg Injection.
What are the side effects of Dobutamine?
Increased Heart Rate, Blood Pressure, and Ventricular Ectopic Activity A 10 to 20-mm Hg increase in systolic blood pressure and an increase in heart rate of 5 to 15 beats/minute have been noted in most patients (see WARNINGS regarding exaggerated chronotropic and pressor effects).
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. A catalog listing does not guarantee that a medicine is in stock at any pharmacy.
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