Inapure 5mg Tablet

Adult patients Starting dose is 2.5 (vulnerable adults) or 5 mg twice daily with food. After 2 weeks of treatment, adjust dose based on heart rate. The maximum dose is 7.5 mg twice daily.

Directions from the U.S. FDA-approved label for Ivabradine — your doctor or pharmacist may advise differently.

Ivabradine is contraindicated in patients with: Acute decompensated heart failure, Clinically significant hypotension, Sick sinus syndrome, sinoatrial block or 3 rd degree AV block, unless a functioning demand pacemaker is present, Clinically significant bradycardia, Severe hepatic impairment, Pacemaker dependence (heart rate maintained exclusively by the pacemaker), Concomitant use of strong cytochrome P450 3A4 (CYP3A4) inhibitors, Acute decompensated heart failure, Clinically significant hypotension, Sick sinus syndrome…

Excerpt from the U.S. FDA-approved label for Ivabradine. Talk to a pharmacist or doctor before use.

Fetal toxicity: Females should use effective contraception., Monitor patients for atrial fibrillation., Monitor heart rate decreases and bradycardia symptoms during treatment., Not recommended in patients with 2 nd degree AV block. 5.1 Fetal Toxicity Ivabradine may cause fetal toxicity when administered to a pregnant woman based on findings in animal studies. Embryo-fetal toxicity and cardiac teratogenic effects were observed in fetuses of pregnant rats treated during organogenesis at exposures 1 to 3 times the human exposures (AUC 0-24hr ) at the maximum recommended human dose (MRHD).

Warnings and precautions excerpt from the U.S. FDA-approved label for Ivabradine — not a complete list. Talk to a pharmacist or doctor before use.

Clinically significant adverse reactions that appear in other sections of the labeling include: Atrial Fibrillation, Bradycardia and Conduction Disturbances Most common adverse reactions occurring in ≥ 1% of patients are bradycardia, hypertension, atrial fibrillation and luminous phenomena (phosphenes).

Excerpt from the U.S. FDA-approved label for Ivabradine — not a complete list. Talk to a pharmacist or doctor about side effects.

3 brands · 2 makers in the NepalDoc catalog — see the full Ivabradine guide →

Storage Store at 25°C (77°F);

Storage information from the U.S. FDA-approved label for Ivabradine.