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Kemocarb 150mg Injection

Generic: Carboplatin 150mg
Injection150mg8 brands · 4 makers in Nepal
Kemocarb is Carboplatin 150mg made by Fresenius Kabi pharmaceuticals.
BrandKemocarb
Generic nameCarboplatin
MakerFresenius Kabi pharmaceuticals
FormInjection
Strength150mg
Source / स्रोतNepalDoc medicine catalog

What it's for

Initial Treatment of Advanced Ovarian Carcinoma Carboplatin Injection is indicated for the initial treatment of advanced ovarian carcinoma in established combination with other approved chemotherapeutic agents. One established combination regimen consists of Carboplatin Injection and cyclophosphamide.

From the U.S. FDA-approved label for Carboplatin. Full label: DailyMed.

Initial Treatment of Advanced Ovarian Carcinoma Carboplatin Injection is indicated for the initial treatment of advanced ovarian carcinoma in established combination with other approved chemotherapeutic agents. One established combination regimen consists of Carboplatin Injection and cyclophosphamide. Two randomized controlled studies conducted by the NCIC and SWOG with carboplatin versus cisplatin, both in combination with cyclophosphamide, have demonstrated equivalent overall survival between the two groups (see CLINICAL STUDIES ). There is limited statistical power to demonstrate equivalence in overall pathologic complete response rates and long-term survival (≥ 3 years) because of the small number of patients with these outcomes: the small number of patients with residual tumor <2 cm after initial surgery also limits the statistical power to demonstrate equivalence in this subgroup. Secondary Treatment of Advanced Ovarian Carcinoma Carboplatin Injection is indicated for the palliative treatment of patients with ovarian carcinoma recurrent after prior chemotherapy, including patients who have been previously treated with cisplatin.

From the U.S. FDA-approved label for Carboplatin. Full label: DailyMed.

Single Agent Therapy Carboplatin Injection, as a single agent, has been shown to be effective in patients with recurrent ovarian carcinoma at a dosage of 360 mg/m 2 IV on day 1 every 4 weeks (alternatively see Formula Dosing ). Combination Therapy with Cyclophosphamide In the chemotherapy of advanced ovarian cancer, an effective combination for previously untreated patients consists of: Carboplatin Injection - 300 mg/m 2 IV on day 1 every four weeks for six cycles (alternatively see Formula Dosing ). Cyclophosphamide - 600 mg/m 2 IV on day 1 every four weeks for six cycles.

Directions from the U.S. FDA-approved label for Carboplatin — your doctor or pharmacist may advise differently.

Carboplatin Injection is contraindicated in patients with a history of severe allergic reactions to cisplatin or other platinum-containing compounds. Carboplatin Injection should not be employed in patients with severe bone marrow depression or significant bleeding.

Excerpt from the U.S. FDA-approved label for Carboplatin. Talk to a pharmacist or doctor before use.

Bone marrow suppression (leukopenia, neutropenia, and thrombocytopenia) is dose-dependent and is also the dose-limiting toxicity. Peripheral blood counts should be frequently monitored during carboplatin treatment and, when appropriate, until recovery is achieved. Median nadir occurs at day 21 in patients receiving single agent carboplatin. In general, single intermittent courses of carboplatin should not be repeated until leukocyte, neutrophil, and platelet counts have recovered.

Warnings and precautions excerpt from the U.S. FDA-approved label for Carboplatin — not a complete list. Talk to a pharmacist or doctor before use.

For a comparison of toxicities when carboplatin or cisplatin was given in combination with cyclophosphamide, see CLINICAL STUDIES: Use with Cyclophosphamide for Initial Treatment of Ovarian Cancer: Comparative Toxicity.

Excerpt from the U.S. FDA-approved label for Carboplatin — not a complete list. Talk to a pharmacist or doctor about side effects.

Carbotin 150mg InjectionGetwell Pharmaceuticals
Carbotin 450mg InjectionGetwell Pharmaceuticals
Kemocarb 450mg InjectionFresenius Kabi pharmaceuticals

8 brands · 4 makers in the NepalDoc catalog — see the full Carboplatin guide →

Unopened vials of Carboplatin Injection are stable to the date indicated on the package when stored at 25°C (77°F); excursions permitted from 15°–30°C (59°–86°F). Protect from light. Carboplatin Injection multiple-dose vials maintain microbial, chemical, and physical stability for up to 14 days at 25°C following multiple needle entries.

Storage information from the U.S. FDA-approved label for Carboplatin.

Questions & answers

What is Kemocarb?

Kemocarb 150mg Injection is a Carboplatin medicine made by Fresenius Kabi pharmaceuticals. It comes as 150mg Injection.

What is Kemocarb used for?

According to its FDA label, Carboplatin is used for the initial treatment of advanced ovarian carcinoma in established combination with other approved chemotherapeutic agents.

What is the generic name of Kemocarb?

The generic name of Kemocarb is Carboplatin.

Which brands of Carboplatin are available in Nepal?

8 brands of Carboplatin are listed in the NepalDoc catalog, from 4 makers — including Carboplatin 150mg Injection, Carboplatin 450mg Injection, Carbotin 150mg Injection, Carbotin 450mg Injection, Cytocarb 150mg Injection, Cytocarb 450mg Injection.

What are the side effects of Carboplatin?

For a comparison of toxicities when carboplatin or cisplatin was given in combination with cyclophosphamide, see CLINICAL STUDIES: Use with Cyclophosphamide for Initial Treatment of Ovarian Cancer: Comparative Toxicity.

Full medicine guide Check on Medicine Board
+ Safety information

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