Dactinomycin is used for: Wilms Tumor; Rhabdomyosarcoma; Ewing Sarcoma; Gestational Trophoblastic Neoplasms; Testicular Cancer.
Recorded in the NepalDoc medicine catalog for Dactinomycin.
Dactinomycin for Injection is an actinomycin indicated for the treatment of: adult and pediatric patients with Wilms tumor, as part of a multi-phase, combination chemotherapy regimen. adult and pediatric patients with rhabdomyosarcoma, as part of a multi-phase, combination chemotherapy regimen.
From the U.S. FDA-approved label for Dactinomycin. Full label: DailyMed.
Dactinomycin for Injection is an actinomycin indicated for the treatment of: adult and pediatric patients with Wilms tumor, as part of a multi-phase, combination chemotherapy regimen. adult and pediatric patients with rhabdomyosarcoma, as part of a multi-phase, combination chemotherapy regimen. post-menarchal patients with gestational trophoblastic neoplasia, as a single agent or as part of a combination chemotherapy regimen. adult patients with locally recurrent or locoregional solid malignancies, as a component of palliative or adjunctive regional perfusion.
From the U.S. FDA-approved label for Dactinomycin. Full label: DailyMed.
Wilms Tumor: The recommended dose is 45 mcg/kg intravenously once every 3 to 6 weeks for up to 26 weeks, as part of a multi-agent combination chemotherapy regimen. Rhabdomyosarcoma: The recommended dose is 15 mcg/kg intravenously once daily for 5 days every 3 to 9 weeks for up to 112 weeks, as part of a multi-agent combination chemotherapy regimen. Ewing Sarcoma: The recommended dose is 1,250 mcg/m 2 intravenously once every 3 weeks for 51 weeks, as part of a multi-agent combination chemotherapy regimen.
Directions from the U.S. FDA-approved label for Dactinomycin — your doctor or pharmacist may advise differently.
Secondary Malignancy or Leukemia: Increased risk of secondary malignancies following treatment. Veno-occlusive Disease: Can cause severe or fatal VOD. Monitor for elevations in AST, ALT, total bilirubin, hepatomegaly, weight gain, or ascites. Consider delaying next dose. Extravasation: Immediately interrupt the injection or infusion and apply ice. Myelosuppression: Monitor blood cell counts before each cycle. Delay next dose if severe myelosuppression has not improved. Immunizations: Vaccination with live viral vaccines is not recommended before or during treatment.
Warnings and precautions excerpt from the U.S. FDA-approved label for Dactinomycin — not a complete list. Talk to a pharmacist or doctor before use.
The following serious adverse reactions are described elsewhere in the labeling: Secondary Malignancy and Leukemia Veno-occlusive Disease Extravasation Myelosuppression Immunizations Severe Mucocutaneous Reactions Renal Toxicity Hepatotoxicity Potentiation of Radiation Toxicity and Radiation Recall Common adverse reactions are: infection, alopecia, rash, dysphagia, fatigue, fever, nausea, vomiting, anemia, neutropenia,…
Excerpt from the U.S. FDA-approved label for Dactinomycin — not a complete list. Talk to a pharmacist or doctor about side effects.
Conditions Store at 20° to 25°C (68° to 77°F); excursions permitted between 15° to 30°C (59° to 86°F). Protect from light and humidity. Store the reconstituted Dactinomycin for Injection, USP at room temperature for no more than 4 hours from reconstitution to completion of administration. Dactinomycin for Injection, USP is a cytotoxic drug.
Storage information from the U.S. FDA-approved label for Dactinomycin.
What is Tinowel?
Tinowel Injection is a Dactinomycin medicine made by Getwell Pharmaceuticals. It comes as Injection.
What is Tinowel used for?
Dactinomycin is used for Wilms Tumor, Rhabdomyosarcoma, Ewing Sarcoma, Gestational Trophoblastic Neoplasms, Testicular Cancer.
What is the generic name of Tinowel?
The generic name of Tinowel is Dactinomycin.
What are the side effects of Dactinomycin?
The following serious adverse reactions are described elsewhere in the labeling: Secondary Malignancy and Leukemia Veno-occlusive Disease Extravasation Myelosuppression Immunizations Severe Mucocutaneous Reactions Renal Toxicity Hepatotoxicity Potentiation of Radiation Toxicity and Radiation Recall Common adverse reactions are: infection, alopecia, rash, dysphagia, fatigue, fever, nausea, vomiting, anemia, neutropenia,…
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. A catalog listing does not guarantee that a medicine is in stock at any pharmacy.
