Desvenlafaxine

Recommended dose: 50 mg once daily with or without food. There was no evidence that doses greater than 50 mg per day confer any additional benefit. The 25 mg per day dose is intended for a gradual reduction in dose when discontinuing treatment or dosing in severe renal and end-stage renal disease patients.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Hypersensitivity to desvenlafaxine succinate, venlafaxine hydrochloride or to any excipients in the desvenlafaxine extended-release tablets formulation. Angioedema has been reported in patients treated with desvenlafaxine extended-release tablets. The use of MAOIs intended to treat psychiatric disorders with desvenlafaxine extended-release tablets or within 7 days of stopping treatment with desvenlafaxine extended-release tablets is contraindicated because of an increased risk of serotonin syndrome.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. If it occurs, discontinue desvenlafaxine extended-release tablets and serotonergic agents and initiate supportive treatment. Elevated Blood Pressure: Control hypertension before initiating treatment. Monitor blood pressure regularly during treatment. Increased Risk of Bleeding: Concomitant use of aspirin, NSAIDs, other antiplatelet drugs, warfarin, and other anticoagulants may increase this risk.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

The following adverse reactions are discussed in greater detail in other sections of the label. Hypersensitivity Suicidal Thoughts and Behaviors in Pediatric and Young Adult Patients Serotonin Syndrome Elevated Blood Pressure Increased Risk of Bleeding Angle Closure Glaucoma Activation of Mania/Hypomania Discontinuation Syndrome Seizure Hyponatremia Interstitial Lung Disease and Eosinophilic Pneumonia Sexual Dysfunction Most…

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

137 products from 77 makers in the NepalDoc medicine catalog use this generic:

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Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Store at 20° to 25°C (68° to 77°F);

Storage information from the U.S. FDA-approved label.