Levocarnitine oral solution is indicated in the treatment of primary systemic carnitine deficiency. In the reported cases, the clinical presentation consisted of recurrent episodes of Reye-like encephalopathy, hypoketotic hypoglycemia, and/or cardiomyopathy.
From the U.S. FDA-approved label for Levocarnitine. Full label: DailyMed.
Levocarnitine oral solution is indicated in the treatment of primary systemic carnitine deficiency. In the reported cases, the clinical presentation consisted of recurrent episodes of Reye-like encephalopathy, hypoketotic hypoglycemia, and/or cardiomyopathy. Associated symptoms included hypotonia, muscle weakness and failure to thrive. A diagnosis of primary carnitine deficiency requires that serum, red cell and/or tissue carnitine levels be low and that the patient does not have a primary defect in fatty acid or organic acid oxidation (see CLINICAL PHARMACOLOGY ). In some patients, particularly those presenting with cardiomyopathy, carnitine supplementation rapidly alleviated signs and symptoms. Treatment should include, in addition to carnitine, supportive and other therapy as indicated by the condition of the patient.
From the U.S. FDA-approved label for Levocarnitine. Full label: DailyMed.
For oral use only. Not for parenteral use. Adults: The recommended dosage of levocarnitine is 1 to 3 g/day for a 50 kg subject, which is equivalent to 10 to 30 mL/day of levocarnitine oral solution.
Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.
None known.
Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.
Hypersensitivity Reactions Serious hypersensitivity reactions, including rash, urticaria, and facial edema have been reported with oral levocarnitine. Other serious hypersensitivity reactions, including anaphylaxis, laryngeal edema, and bronchospasm have been reported following intravenous levocarnitine administration, mostly in patients with end-stage renal disease undergoing dialysis. Discontinue use of levocarnitine and instruct patients to seek medical attention if they experience symptoms suggestive of a hypersensitivity reaction.
Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.
The following adverse reactions associated with the use of oral formulations of levocarnitine were identified in clinical trials or postmarketing reports. Because these reactions were reported voluntarily from a population of uncertain size, it is not always possible to estimate their frequency, reliability, or to establish a causal relationship to drug exposure.
Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.
6 products from 4 makers in the NepalDoc medicine catalog use this generic:
| Brand | Composition | Maker | Pack |
|---|---|---|---|
| Carnisure 330mg Tablet | Levocarnitine (330mg) | Elder Pharmaceuticals. | |
| Carnisure 500mg Tablet | Levocarnitine (500mg) | Torrent Pharmaceuticals Ltd. | |
| Carnisure 500mg/5ml Injection | Levocarnitine (500mg/5ml) | Torrent Pharmaceuticals Ltd. | |
| Carnitor 500mg Tablet | Levocarnitine (500mg) | Win-Medicare Pvt. Ltd. | |
| Carnitor Syrup | Levocarnitine | Elder Pharmaceuticals. | |
| Nucarnit 330MG Tablet | Levocarnitine (330MG) | Emcure Pharmaceuticals Ltd. |
Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.
Store at controlled room temperature 15º to 30 ºC (59º to 86º F).
Storage information from the U.S. FDA-approved label.
Levocarnitine is recorded in the NepalDoc medicine catalog for: Congestive heart failure, Diabetic nephropathy, Intermittent claudication, Kidney disease, Chronic Fatigue Syndrome, Heart Diseases.
For Congestive heart failure: Hydrochlorothiazide, Hydrochlorothiazide + Ramipril, Indapamide, Ramipril.
For Diabetic nephropathy: Hydrochlorothiazide + Ramipril, Hydrochlorothiazide + Telmisartan, Olmesartan medoxomil, Telmisartan.
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. A catalog listing does not guarantee that a medicine is in stock at any pharmacy.
