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Paclitaxel

Microtubule inhibitor
Powder · Injection6 mg · 5 ml · 17 ml146 brands · 53 makers
Paclitaxel is a microtubule inhibitor. Paclitaxel is a microtubule inhibitor indicated for the treatment of: Metastatic breast cancer, after failure of combination chemotherapy for metastatic disease or relapse within 6 months of adjuvant chemotherapy. Paclitaxel is listed in Nepal's National List of Essential Medicines (NLEM, Sixth Revision 2021) under Immunomodulators, Antineoplastic and Medicines used in Palliative Care.
Generic namepaclitaxel
Therapeutic classImmunomodulators, Antineoplastic and Medicines used in Palliative Care > 8.2.1 Cytotoxic medicines (complementary list)
Form & strength (NLEM)Powder for injection: 6 mg/ ml in 5 ml, 17 ml
Source / स्रोतNational List of Essential Medicines Nepal (2021); NepalDoc medicine catalog

What it's for

Paclitaxel is a microtubule inhibitor indicated for the treatment of: Metastatic breast cancer, after failure of combination chemotherapy for metastatic disease or relapse within 6 months of adjuvant chemotherapy. Prior therapy should have included an anthracycline unless clinically contraindicated.

From the U.S. FDA-approved label for Paclitaxel. Full label: DailyMed.

Paclitaxel is a microtubule inhibitor indicated for the treatment of: Metastatic breast cancer, after failure of combination chemotherapy for metastatic disease or relapse within 6 months of adjuvant chemotherapy. Prior therapy should have included an anthracycline unless clinically contraindicated. Locally advanced or metastatic non-small cell lung cancer (NSCLC), as first-line treatment in combination with carboplatin, in patients who are not candidates for curative surgery or radiation therapy. Metastatic adenocarcinoma of the pancreas as first-line treatment, in combination with gemcitabine.

From the U.S. FDA-approved label for Paclitaxel. Full label: DailyMed.

Do not substitute paclitaxel protein-bound particles for injectable suspension (albumin-bound) for other paclitaxel products. Extravasation: Closely monitor the infusion site for extravasation and infiltration. Metastatic Breast Cancer (MBC): Recommended dosage of paclitaxel protein-bound particles for injectable suspension (albumin-bound) is 260 mg/m2 intravenously over 30 minutes every 3 weeks.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Paclitaxel protein-bound particles for injectable suspension (albumin-bound) is contraindicated in patients with: Baseline neutrophil counts of < 1,500 cells/mm 3 A history of severe hypersensitivity reactions to paclitaxel protein-bound particles for injectable suspension (albumin-bound). Neutrophil counts of < 1,500 cells/mm 3. Severe hypersensitivity reactions to paclitaxel.

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

Sensory neuropathy occurs frequently and may require dose reduction or treatment interruption. Sepsis occurred in patients with or without neutropenia who received paclitaxel protein-bound particles for injectable suspension (albumin-bound) in combination with gemcitabine; interrupt paclitaxel protein-bound particles for injectable suspension (albumin-bound) and gemcitabine until sepsis resolves, and if neutropenia, until neutrophils are at least 1500 cells/mm 3, then resume treatment at reduced dose levels.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

146 products from 53 makers in the NepalDoc medicine catalog use this generic:

BrandCompositionMakerPack
C-Celtax 260MG/43.3ML InjectionPaclitaxel (260MG/43.3ML)Celon Lab
Intaxel 260 260mg TabletPaclitaxel (260mg)Fresenius Kabi pharmaceuticals
Mitotax 100mg/ml InjectionPaclitaxel (100mg/ml)Dr. Reddy&#039;s Laboratories.
Mitotax 250mg/ml InjectionPaclitaxel (250mg/ml)Dr. Reddy&#039;s Laboratories.
Paclitax 100 100mg InjectionPaclitaxel (100mg)Cipla Ltd.
Paclitax 260 260mg InjectionPaclitaxel (260mg)Cipla Ltd.
Paclitax 30 30mg InjectionPaclitaxel (30mg)Cipla Ltd.
Pacliwel 100mg/ml InjectionPaclitaxel (100mg/ml)Getwell Pharmaceuticals
Pacliwel 260mg InjectionPaclitaxel (260mg)Getwell Pharmaceuticals
Pacliwel 30mg/ml InjectionPaclitaxel (30mg/ml)Getwell Pharmaceuticals
Petaxel 100 100mg InjectionPaclitaxel (100mg)Biochem Pharmaceuticals Industries Limited.
Petaxel 260 260mg InjectionPaclitaxel (260mg)Biochem Pharmaceuticals Industries Limited.
Petaxel 30 30gm InjectionPaclitaxel (30gm)Biochem Pharmaceuticals Industries Limited.
AB-Pacli 100mg InjectionPaclitaxel (100mg)Adley Formulationsvial of 1 Injection
Abra Bound Suspension for InjectionPaclitaxel (1000mg)Arechar Healthcarevial of 1 Suspension for Injection
Abraxane 100mg InjectionPaclitaxel (100mg)Bioconvial of 1 Injection
Acopacli 100 InjectionPaclitaxel (100mg)Accord Pharmaceuticalsvial of 16.7 ml Injection
Acopacli 260 InjectionPaclitaxel (260mg)Accord Pharmaceuticalsvial of 1 Injection
Acopacli 30 InjectionPaclitaxel (30mg)Accord Pharmaceuticalsvial of 5 ml Injection
Adpaxil 100mg InjectionPaclitaxel (100mg)Adley Formulationsvial of 16.7 ml Injection
Adpaxil 260mg/43.4ml InjectionPaclitaxel (6mg/ml)Adley Formulationsvial of 43.4 ml Injection
Adpaxil 300mg InjectionPaclitaxel (300mg)Adley Formulationsvial of 1 Injection
Adpaxil 30mg/5ml InjectionPaclitaxel (6mg/ml)Adley Formulationsvial of 5 ml Injection
Albumaps 100mg InjectionPaclitaxel (100mg)AMPS Biotech Pvt Ltdvial of 1 Injection
Altaxel 100mg InjectionPaclitaxel (100mg)Alkem Laboratories Ltdvial of 1 Injection
Altaxel 250mg InjectionPaclitaxel (250mg)Alkem Laboratories Ltdvial of 1 Injection
Altaxel 260mg InjectionPaclitaxel (260mg)Alkem Laboratories Ltdvial of 1 Injection
Altaxel 300mg InfusionPaclitaxel (300mg)Alkem Laboratories Ltdbottle of 50 ml Infusion
Altaxel 30mg InjectionPaclitaxel (30mg)Alkem Laboratories Ltdvial of 1 Injection
Altaxel Nova 100mg InjectionPaclitaxel (100mg)Alkem Laboratories Ltdvial of 1 Injection

Showing 30 of 146 catalog products. Search the full catalog in the app.

Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Protect from bright light.

Storage information from the U.S. FDA-approved label.

Medicines for the same conditions

Paclitaxel is recorded in the NepalDoc medicine catalog for: Ovarian carcinoma, Breast cancer, Lung cancer, Kaposi's sarcoma.

For Breast cancer: Capecitabine, Epirubicin, Letrozole, Melphalan, Norethisterone, Tamoxifen.

For Lung cancer: Gemcitabine.

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+ Safety information

This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.

NepalDoc — Nepal's Healthcare Super-App (Beta) / नेपालको स्वास्थ्य सुपर-एप (बेटा).
Medicine information only — not medical advice. Confirm with a pharmacist or doctor.