Major Depressive Disorder – Sertraline hydrochloride is indicated for the treatment of major depressive disorder in adults. The efficacy of Sertraline hydrochloride in the treatment of a major depressive episode was established in six to eight week controlled trials of adult outpatients whose diagnoses corresponded most closely to the DSM-III category of major depressive disorder (see Clinical Trials under CLINICAL PHARMACOLOGY ).
From the U.S. FDA-approved label for Sertraline. Full label: DailyMed.
Major Depressive Disorder – Sertraline hydrochloride is indicated for the treatment of major depressive disorder in adults. The efficacy of Sertraline hydrochloride in the treatment of a major depressive episode was established in six to eight week controlled trials of adult outpatients whose diagnoses corresponded most closely to the DSM-III category of major depressive disorder (see Clinical Trials under CLINICAL PHARMACOLOGY ). A major depressive episode implies a prominent and relatively persistent depressed or dysphoric mood that usually interferes with daily functioning (nearly every day for at least 2 weeks); it should include at least 4 of the following 8 symptoms: change in appetite, change in sleep, psychomotor agitation or retardation, loss of interest in usual activities or decrease in sexual drive, increased fatigue, feelings of guilt or worthlessness, slowed thinking or impaired concentration, and a suicide attempt or suicidal ideation. The antidepressant action of sertraline hydrochloride in hospitalized depressed patients has not been adequately studied.
From the U.S. FDA-approved label for Sertraline. Full label: DailyMed.
Initial Treatment Dosage for Adults Major Depressive Disorder –Sertraline hydrochloride treatment should be administered at a dose of 50 mg once daily. While a relationship between dose and effect has not been established for major depressive disorder, OCD, panic disorder, PTSD or social anxiety disorder, patients were dosed in a range of 50-200 mg/day in the clinical trials demonstrating the effectiveness of Sertraline hydrochloride for the treatment of this indication. Consequently, a dose of 50 mg, administered once daily, is recommended as the initial therapeutic dose.
Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.
All Dosage Forms of Sertraline: The use of MAOIs intended to treat psychiatric disorders with Sertraline hydrochloride or within 14 days of stopping treatment with Sertraline hydrochloride is contraindicated because of an because of an increased risk if serotonin syndrome. The use of Sertraline hydrochloride within 14 days of stopping an MAOI intended to treat psychiatric disorders is also contraindicated (see WARNINGS and DOSAGE AND ADMINISTRATION ).
Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.
Clinical Worsening and Suicide Risk Patients with major depressive disorder (MDD), both adult and pediatric, may experience worsening of their depression and/or the emergence of suicidal ideation and behavior (suicidality) or unusual changes in behavior, whether or not they are taking antidepressant medications, and this risk may persist until significant remission occurs. Suicide is a known risk of depression and certain other psychiatric disorders, and these disorders themselves are the strongest predictors of suicide.
Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.
During its premarketing assessment, multiple doses of sertraline hydrochloride were administered to over 4000 adult subjects as of February 18, 2000.
Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.
327 products from 174 makers in the NepalDoc medicine catalog use this generic:
| Brand | Composition | Maker | Pack |
|---|---|---|---|
| Actiser 50mg Tablet | Sertraline (50mg) | Unimarck Healthcare Ltd | strip of 10 tablets |
| Aderta 50mg Tablet | Sertraline (50mg) | Shinto Organics (P) Limited | strip of 10 tablets |
| Alsert 50mg Tablet | Sertraline (50mg) | Altar Pharmaceuticals Pvt Ltd | strip of 10 tablets |
| Aniser 50mg Tablet | Sertraline (50mg) | Anikem Laboratories | strip of 10 tablets |
| Artraline 50mg Tablet | Sertraline (50mg) | Arpsy Life Science Private Limited | strip of 10 tablets |
| Atline 100mg Tablet | Sertraline (100mg) | Octane Biotech Pvt Ltd | strip of 10 tablets |
| Atraline 50mg Tablet | Sertraline (50mg) | Ambreyo Lifesciences | strip of 10 tablets |
| Bioserene 50mg Tablet | Sertraline (50mg) | Paradigm Healthcare | strip of 10 tablets |
| Biosert 50mg Tablet | Sertraline (50mg) | Biochem Pharmaceutical Industries | strip of 10 tablets |
| Censir 50mg Tablet | Sertraline (50mg) | Sanify Healthcare Pvt Ltd | strip of 10 tablets |
| Centrol 100 Tablet | Sertraline (100mg) | Holy Evolution Pharma | strip of 10 tablets |
| Centrol 25 Tablet | Sertraline (25mg) | Holy Evolution Pharma | strip of 10 tablets |
| Cnsert 100mg Tablet | Sertraline (100mg) | CNX Healthcare Pvt Ltd | strip of 10 tablets |
| Cnsert 25mg Tablet | Sertraline (25mg) | CNX Healthcare Pvt Ltd | strip of 10 tablets |
| Cnsert 50mg Tablet | Sertraline (50mg) | CNX Healthcare Pvt Ltd | strip of 10 tablets |
| Cusert 50mg Tablet | Sertraline (50mg) | Curasia Medilabs | strip of 10 tablets |
| DavaIndia Sertraline 50mg Tablet | Sertraline (50mg) | Davaindia Generic Pharmacy | strip of 10 tablets |
| Daxid 100mg Tablet | Sertraline (100mg) | Pfizer Ltd | strip of 15 tablets |
| Daxid 25mg Tablet | Sertraline (25mg) | Pfizer Ltd | strip of 15 tablets |
| Daxid 50mg Tablet | Sertraline (50mg) | Pfizer Ltd | strip of 15 tablets |
| Dazline 50mg Tablet | Sertraline (50mg) | Novalab Healthcare Pvt Ltd | strip of 10 tablets |
| Dazolin 50mg Tablet | Sertraline (50mg) | Daksh Pharma Pvt Ltd | strip of 10 tablets |
| Denzy 100mg Tablet | Sertraline (100mg) | BRD MediLabs | strip of 10 tablets |
| Denzy 50mg Tablet | Sertraline (50mg) | BRD MediLabs | strip of 10 tablets |
| Deplin 50mg Tablet | Sertraline (50mg) | Sykocure Lifesciences | strip of 10 tablets |
| Depsar 25mg Tablet | Sertraline (25mg) | Laxian Healthcare | strip of 10 tablets |
| Depsert 100mg Tablet | Sertraline (100mg) | Reliance Formulation Pvt Ltd | strip of 10 tablets |
| Depsert 50mg Tablet | Sertraline (50mg) | Reliance Formulation Pvt Ltd | strip of 10 tablets |
| Dexsar Tablet | Sertraline (50mg) | Regent Ajanta Biotech | strip of 10 tablets |
| Eccite 50mg Tablet | Sertraline (50mg) | Morepen Laboratories Ltd | strip of 10 tablets |
Showing 30 of 327 catalog products. Search the full catalog in the app.
Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.
Store at 20°C to 25°C (68°F to 77°F).
Storage information from the U.S. FDA-approved label.
Sertraline is recorded in the NepalDoc medicine catalog for: Major Depressive illness, Panic disorder, Premenstrual dysphoric disorder, Post-traumatic stress disorder, Obsessive-compulsive disorder, Social anxiety disorder.
For Panic disorder: Escitalopram oxalate, Paroxetine, Venlafaxine.
For Obsessive-compulsive disorder: Paroxetine.
For Social anxiety disorder: Paroxetine, Venlafaxine.
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. A catalog listing does not guarantee that a medicine is in stock at any pharmacy.
