SOVALDI is a hepatitis C virus (HCV) nucleotide analog NS5B polymerase inhibitor indicated for the treatment of: Adult patients with genotype 1, 2, 3 or 4 chronic HCV infection without cirrhosis or with compensated cirrhosis as a component of a combination antiviral treatment regimen. Pediatric patients 3 years of age and older with genotype 2 or 3 chronic HCV infection without cirrhosis or with compensated cirrhosis in combination with ribavirin.
From the U.S. FDA-approved label for Sofosbuvir. Full label: DailyMed.
SOVALDI is a hepatitis C virus (HCV) nucleotide analog NS5B polymerase inhibitor indicated for the treatment of: Adult patients with genotype 1, 2, 3 or 4 chronic HCV infection without cirrhosis or with compensated cirrhosis as a component of a combination antiviral treatment regimen. Pediatric patients 3 years of age and older with genotype 2 or 3 chronic HCV infection without cirrhosis or with compensated cirrhosis in combination with ribavirin.
From the U.S. FDA-approved label for Sofosbuvir. Full label: DailyMed.
Testing Prior to the Initiation of Therapy: Test all patients for HBV infection by measuring HBsAg and anti-HBc. Recommended dosage in adults: One 400 mg tablet taken once daily with or without food. Recommended dosage in pediatric patients 3 years of age and older: Recommended dosage of SOVALDI in pediatric patients 3 years of age and older with genotype 2 or 3 HCV using SOVALDI tablets or oral pellets is based on weight.
Directions from the U.S. FDA-approved label for Sofosbuvir — your doctor or pharmacist may advise differently.
When SOVALDI is used in combination with ribavirin or peginterferon alfa/ribavirin, the contraindications applicable to those agents are applicable to combination therapies. Refer to the prescribing information of peginterferon alfa and ribavirin for a list of their contraindications. When used in combination with peginterferon alfa/ribavirin or ribavirin alone, all contraindications to peginterferon alfa and/or ribavirin also apply to SOVALDI combination therapy.
Excerpt from the U.S. FDA-approved label for Sofosbuvir. Talk to a pharmacist or doctor before use.
Risk of Hepatitis B Virus Reactivation: Test all patients for evidence of current or prior HBV infection before initiation of HCV treatment. Monitor HCV/HBV coinfected patients for HBV reactivation and hepatitis flare during HCV treatment and post-treatment follow-up. Initiate appropriate patient management for HBV infection as clinically indicated.
Warnings and precautions excerpt from the U.S. FDA-approved label for Sofosbuvir — not a complete list. Talk to a pharmacist or doctor before use.
The following serious adverse reactions are described below and elsewhere in the labeling: Serious Symptomatic Bradycardia When Coadministered with Amiodarone. The most common adverse events (incidence greater than or equal to 20%, all grades) observed with SOVALDI in combination with ribavirin were fatigue and headache.
Excerpt from the U.S. FDA-approved label for Sofosbuvir — not a complete list. Talk to a pharmacist or doctor about side effects.
3 brands · 3 makers in the NepalDoc catalog — see the full Sofosbuvir guide →
Store below 30 °C (86 °F). Dispense only in original container Do not use if seal over bottle opening is broken or missing
Storage information from the U.S. FDA-approved label for Sofosbuvir.
What is Sofuvir?
Sofuvir 400mg Tablet is a Sofosbuvir medicine made by Magnus Pharma Pvt. Ltd. It comes as 400mg Tablet.
What is the generic name of Sofuvir?
The generic name of Sofuvir is Sofosbuvir.
Which brands of Sofosbuvir are available in Nepal?
3 brands of Sofosbuvir are listed in the NepalDoc catalog, from 3 makers — including Hepcivir 400mg Tablet, Sofovir 400mg Tablet.
What are the side effects of Sofosbuvir?
The following serious adverse reactions are described below and elsewhere in the labeling: Serious Symptomatic Bradycardia When Coadministered with Amiodarone. The most common adverse events (incidence greater than or equal to 20%, all grades) observed with SOVALDI in combination with ribavirin were fatigue and headache.
This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. A catalog listing does not guarantee that a medicine is in stock at any pharmacy.
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