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Zidovudine (ZDV or AZT)

Nucleoside analogue reverse transcriptase inhibitor
Tablet50 mg · 5 ml · 300 mg23 brands · 11 makers
Zidovudine (ZDV or AZT) is a nucleoside analogue reverse transcriptase inhibitor used for treatment of Human Immunodeficiency Virus (HIV-1) infection in combination with other antiretroviral agents.. Zidovudine (ZDV or AZT) is listed in Nepal's National List of Essential Medicines (NLEM, Sixth Revision 2021) under Anti-Infective Medicines.
Generic namezidovudine (ZDV or AZT)
Therapeutic classAnti-Infective Medicines > 6.4.2.1 Nucleoside/Nucleosite reverse transcriptase inhibitors
Form & strength (NLEM)Oral liquid: 50 mg/ 5 ml; Tablet: 300 mg
Source / स्रोतNational List of Essential Medicines Nepal (2021); NepalDoc medicine catalog

What it's for

Zidovudine tablets are a nucleoside analogue reverse transcriptase inhibitor indicated for: Treatment of Human Immunodeficiency Virus (HIV-1) infection in combination with other antiretroviral agents., Prevention of maternal-fetal HIV-1 transmission.

From the U.S. FDA-approved label for Zidovudine (ZDV or AZT). Full label: DailyMed.

Zidovudine tablets are a nucleoside analogue reverse transcriptase inhibitor indicated for: Treatment of Human Immunodeficiency Virus (HIV-1) infection in combination with other antiretroviral agents., Prevention of maternal-fetal HIV-1 transmission. 1.2 Prevention of Maternal-Fetal HIV-1 Transmission Zidovudine tablets are indicated for the prevention of maternal-fetal HIV-1 transmission. The indication is based on a dosing regimen that included 3 components: 1. antepartum therapy of HIV-1-infected mothers 2.

From the U.S. FDA-approved label for Zidovudine (ZDV or AZT). Full label: DailyMed.

2 DOSAGE & ADMINISTRATION, Treatment of HIV-1 infection: Adults: Recommended oral dosage is 300 mg twice a day with other antiretroviral agents.

Directions from the U.S. FDA-approved label — your doctor or pharmacist may advise differently.

Zidovudine tablets are contraindicated in patients who have had a potentially life-threatening hypersensitivity reaction (e.g., anaphylaxis, Stevens-Johnson syndrome) to any of the components of the formulations. Hypersensitivity to zidovudine or any of the components (e.g., anaphylaxis, Stevens-Johnson syndrome).

Excerpt from the U.S. FDA-approved label. Talk to a pharmacist or doctor before use.

See boxed warning for information about the following: hematologic toxicity, myopathy, and lactic acidosis and severe hepatomegaly, Exacerbation of anemia has been reported in HIV-1/HCV co-infected patients receiving ribavirin and zidovudine. Coadministration of ribavirin and zidovudine is not advised., Hepatic decompensation, (some fatal), has occurred in HIV-1/HCV co-infected patients receiving combination antiretroviral therapy and interferon alfa with/without ribavirin.

Warnings and precautions excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor before use.

The following adverse reactions are discussed in greater detail in other sections of the labeling: Hematologic toxicity, including neutropenia and anemia., Symptomatic myopathy., Lactic acidosis and severe hepatomegaly with steatosis., Hepatic decompensation in patients co-infected with HIV-1 and hepatitis C.

Excerpt from the U.S. FDA-approved label — not a complete list. Talk to a pharmacist or doctor about side effects.

23 products from 11 makers in the NepalDoc medicine catalog use this generic:

BrandCompositionMakerPack
Zidovir 100 100mg CapsuleZidovudine (100mg)Cipla Ltd.
Zidovir 100mg CapsuleZidovudine (100mg)Cipla Ltd.
Zidovir 300mg CapsuleZidovudine (300mg)Cipla Ltd.
Zidovir 300mg TabletZidovudine (300mg)Cipla Ltd.
Zidovir 50 50mg CapsuleZidovudine (50mg)Cipla Ltd.
Viro Z 100mg TabletZidovudine (100mg)Sun Pharmaceutical Industries Ltdstrip of 10 tablets
Viro Z 300mg TabletZidovudine (300mg)Sun Pharmaceutical Industries Ltdstrip of 10 tablets
Ziddivir 100mg TabletZidovudine (100mg)Sain Medicaments Pvt Ltdstrip of 10 tablets
Ziddivir 300mg TabletZidovudine (300mg)Sain Medicaments Pvt Ltdstrip of 10 tablets
Zidine 300mg TabletZidovudine (300mg)Emcure Pharmaceuticals Ltdbottle of 60 tablets
Zido H 100mg CapsuleZidovudine (100mg)Genix Pharma Ltdstrip of 10 capsules
Zidohope 100mg TabletZidovudine (100mg)Macleods Pharmaceuticals Pvt Ltdbottle of 100 tablets
Zidohope 300mg TabletZidovudine (300mg)Macleods Pharmaceuticals Pvt Ltdbottle of 60 tablets
Zidomax 100mg CapsuleZidovudine (100mg)Alkem Laboratories Ltdstrip of 10 capsules
Zidomax 300mg TabletZidovudine (300mg)Alkem Laboratories Ltdstrip of 10 tablets
Zidovex 100mg CapsuleZidovudine (100mg)Veritaz Healthcare Ltdstrip of 10 capsules
Zidovex 300mg CapsuleZidovudine (300mg)Veritaz Healthcare Ltdstrip of 10 capsules
Zidovex L Plus E 300mg TabletZidovudine (300mg)Veritaz Healthcare Ltdstrip of 3 tablets
Zilion 300mg TabletZidovudine (300mg)Cadila Pharmaceuticals Ltdstrip of 10 tablets
Zivudin 100mg TabletZidovudine (100mg)Synmedic Laboratoriesstrip of 10 tablets
Zivudin 300mg TabletZidovudine (300mg)Synmedic Laboratoriesstrip of 10 tablets
Zvd 100mg TabletZidovudine (100mg)Mcneil & Argus Pharmaceuticals Ltdstrip of 10 tablets
Zvd 300mg TabletZidovudine (300mg)Mcneil & Argus Pharmaceuticals Ltdstrip of 10 tablets

Brand list from the NepalDoc medicine catalog. Availability varies by pharmacy — call ahead to confirm stock.

Store at 20° to 25° C (68° to 77°F).

Storage information from the U.S. FDA-approved label.

Medicines for the same conditions

Zidovudine (ZDV or AZT) is recorded in the NepalDoc medicine catalog for: Cancer therapy-induced hyperuricaemia, HIV infection.

For Cancer therapy-induced hyperuricaemia: Allopurinol.

For HIV infection: Efavirenz (EFV or EFZ), Filgrastim, Lamivudine (3TC), Lamivudine + Nevirapine + Zidovudine, Lamivudine + Zidovudine, Nevirapine (NVP), Ritonavir.

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+ Safety information

This page is information only and is not medical advice. Medicine details come from the sources listed above and may change — always confirm the medicine, strength and dose with a pharmacist or doctor before use. NLEM listing does not guarantee that a medicine is in stock at any pharmacy.

NepalDoc — Nepal's Healthcare Super-App (Beta) / नेपालको स्वास्थ्य सुपर-एप (बेटा).
Medicine information only — not medical advice. Confirm with a pharmacist or doctor.